Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746702 | 0.81 | ALOX5AP (0.39) | SCN10AALOX5APFEN1SCN9AKCNN4 | |
| SCHEMBL14746497 | 0.79 | RECQL (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL14744504 | 0.79 | S1PR1 (0.49) | SCN10AALOX5APFEN1SCN9AKCNN4 | |
| SCHEMBL24032682 | 0.77 | POLB (0.62) | SCN10AALOX5APFEN1SCN9A | |
| SCHEMBL30320923 | 0.77 | POLB (0.62) | SCN10AALOX5APFEN1SCN9A | |
| SCHEMBL14746770 | 0.75 | SCN10A (0.50) | SCN10AALOX5APFEN1SCN9AKCNN4 | |
| SCHEMBL14744245 | 0.75 | RORC (0.45) | SCN10AALOX5APFEN1SCN9A | |
| SCHEMBL30321020 | 0.75 | RORC (0.45) | SCN10AALOX5APFEN1SCN9A | |
| SCHEMBL14744102 | 0.73 | RORC (0.49) | SCN10AALOX5APFEN1SCN9AKCNN4 | |
| SCHEMBL14746755 | 0.72 | RORC (0.54) | SCN10AALOX5APFEN1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |