Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2968786 | 0.83 | ALDH1A1 (0.50) | S1PR1ALDH1A1POLBGAAMAPT | |
| SCHEMBL2979005 | 0.82 | ALDH1A1 (0.47) | S1PR1ALDH1A1POLBGAAMAPT | |
| SCHEMBL14746702 | 0.81 | ALOX5AP (0.39) | ALDH1A1KDM4EALOX5APFEN1SCN9A | |
| SCHEMBL14744381 | 0.79 | GAA (0.49) | S1PR1ALDH1A1POLBGAAMAPT | |
| SCHEMBL14747148 | 0.79 | SCN10A (0.41) | ALOX5APFEN1SCN9ASCN10AKCNN4 | |
| SCHEMBL22668889 | 0.75 | MAPT (0.54) | S1PR1GAAMAPTKDM4EKEAP1 | |
| SCHEMBL24032682 | 0.75 | POLB (0.62) | S1PR1POLBGAAMAPTKDM4E | |
| SCHEMBL14744245 | 0.75 | RORC (0.45) | POLBALOX5APFEN1SCN9ASCN10A | |
| SCHEMBL30320923 | 0.75 | POLB (0.62) | S1PR1POLBGAAMAPTKDM4E | |
| SCHEMBL30321020 | 0.75 | RORC (0.45) | POLBALOX5APFEN1SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |