Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744504 | 0.81 | S1PR1 (0.49) | ALOX5APFEN1SCN9ASCN10AKCNN4 | |
| SCHEMBL14747148 | 0.81 | SCN10A (0.41) | ALOX5APFEN1SCN9ASCN10AKCNN4 | |
| SCHEMBL14746703 | 0.79 | SCN10A (0.41) | SCN9ASCN10AALDH1A1SCN5APDK2 | |
| SCHEMBL14744245 | 0.77 | RORC (0.45) | ALOX5APFEN1SCN9ASCN10APDK2 | |
| SCHEMBL30321020 | 0.77 | RORC (0.45) | ALOX5APFEN1SCN9ASCN10APDK2 | |
| SCHEMBL24032682 | 0.77 | POLB (0.62) | ALOX5APFEN1SCN9ASCN10AKDM4E | |
| SCHEMBL30320923 | 0.77 | POLB (0.62) | ALOX5APFEN1SCN9ASCN10AKDM4E | |
| SCHEMBL14744206 | 0.74 | PLA2G7 (0.45) | ALOX5APFEN1SCN9ASCN10AALDH1A1 | |
| SCHEMBL14746783 | 0.73 | KDM4E (0.43) | ALOX5APFEN1SCN9ASCN10AALDH1A1 | |
| SCHEMBL714264 | 0.73 | TSHR (0.48) | ALOX5APFEN1SCN10AALDH1A1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |