Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | PPARD | Q03181 | 9/20 | 0.35 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12242588 | 0.90 | PPARD (0.38) | THRBPPARAPPARDPPARGHDAC6 | |
| SCHEMBL14749473 | 0.90 | PTPN2 (0.34) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL12242587 | 0.89 | THRB (0.41) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL15782789 | 0.85 | HTT (0.43) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL2733945 | 0.80 | PPARD (0.36) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL18200267 | 0.80 | THRB (0.42) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL12213354 | 0.79 | RXRA (0.42) | THRBPPARAPPARDPPARGPTGES | |
| SCHEMBL12242609 | 0.79 | THRB (0.40) | THRBPPARDHPGDCYP2C19 | |
| SCHEMBL18455552 | 0.78 | THRB (0.34) | THRBPPARAPPARDPPARGHPGD | |
| SCHEMBL12242589 | 0.77 | THRB (0.39) | THRBPPARAPPARDPPARGHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130057947-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |