Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733945 | 0.91 | PPARD (0.36) | PTPN2PTPN1TSHRHPGDTHRB | |
| SCHEMBL14749472 | 0.90 | THRB (0.38) | TSHRHPGDTHRBPPARDPPARA | |
| SCHEMBL12242589 | 0.89 | THRB (0.39) | PTPN2PTPN1TSHRHPGDTHRB | |
| SCHEMBL12242587 | 0.86 | THRB (0.41) | TSHRHPGDTHRBPPARDPPARA | |
| SCHEMBL12213987 | 0.84 | THRB (0.40) | PTPN2PTPN1TSHRHPGDTHRB | |
| SCHEMBL15782789 | 0.84 | HTT (0.43) | TSHRHPGDTHRBPPARDPPARA | |
| SCHEMBL12242588 | 0.80 | PPARD (0.38) | THRBPPARDPPARAPPARG | |
| SCHEMBL12213354 | 0.79 | RXRA (0.42) | THRBPPARDPPARAPPARGMAPT | |
| SCHEMBL12242609 | 0.78 | THRB (0.40) | HPGDTHRBPPARDALDH1A1MAPT | |
| SCHEMBL14907522 | 0.77 | POLB (0.38) | PTPN2PTPN1TSHRPTPN6PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130057947-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |