Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782789 | 0.95 | HTT (0.43) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL14749472 | 0.89 | THRB (0.38) | THRBTSHRCYP3A4HPGDTHRA | |
| SCHEMBL18455552 | 0.88 | THRB (0.34) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL16282706 | 0.87 | THRB (0.38) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL19223889 | 0.87 | THRB (0.51) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL14749473 | 0.86 | PTPN2 (0.34) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL18200267 | 0.86 | THRB (0.42) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12213354 | 0.84 | RXRA (0.42) | THRBPPARAPPARDPPARGMAPT | |
| SCHEMBL14588254 | 0.83 | THRB (0.40) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL12242609 | 0.83 | THRB (0.40) | THRBALDH1A1HPGDPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450509-B2 | Liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| EP-3328963-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2019-04-17 | — | — | EP | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| EP-3090033-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-07-04 | — | — | EP | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9315729-B2 | Polymerizable compounds and their use in liquid crystal media and liquid crystal displays | MERCK PATENT GMBH (DE) | 2016-04-19 | — | — | US | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-8895117-B2 | Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays | MERCK PATENT GMBH (DE) | 2014-11-25 | — | — | US | disclosed |
| US-20140225035-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20130057947-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-03-07 | — | — | US | disclosed |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | LPXN, BPHL, MAP1LC3C | THRB 4802/4885TSHR 4818/4885ALDH1A1 3843/4885 |
| US-10450509-B2 | Liquid crystal medium and liquid display | NEFM, CRY1, BMP2 | THRB 3110/4885TSHR 4467/4885ALDH1A1 3890/4885 |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, MAP1LC3C, VCL | THRB 4838/4885TSHR 4869/4885ALDH1A1 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.