Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749472 | 0.90 | THRB (0.38) | PPARDTHRBPPARAPPARGHDAC6 | |
| SCHEMBL2733945 | 0.90 | PPARD (0.36) | PPARDTHRBPPARAPPARGFFAR4 | |
| SCHEMBL12213681 | 0.80 | THRB (0.42) | PPARDTHRBPPARAPPARG | |
| SCHEMBL14749473 | 0.80 | PTPN2 (0.34) | PPARDTHRBPPARAPPARG | |
| SCHEMBL18200267 | 0.80 | THRB (0.42) | PPARDTHRBPPARAPPARGFFAR4 | |
| SCHEMBL12242591 | 0.79 | PPARD (0.39) | PPARDTHRBPPARAPPARGMRGPRX4 | |
| SCHEMBL12242587 | 0.79 | THRB (0.41) | PPARDTHRBPPARAPPARG | |
| SCHEMBL12242605 | 0.79 | PPARD (0.43) | PPARDTHRBPPARAPPARG | |
| SCHEMBL12242589 | 0.77 | THRB (0.39) | PPARDTHRBPPARAPPARGHDAC6 | |
| SCHEMBL14907522 | 0.76 | POLB (0.38) | PPARDPPARAPPARGFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-20160326436-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-11-10 | — | — | US | disclosed |
| US-9475990-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2016-10-25 | — | — | US | disclosed |
| US-9347000-B2 | Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-04-28 | — | — | US | disclosed |
| US-9315729-B2 | Polymerizable compounds and their use in liquid crystal media and liquid crystal displays | MERCK PATENT GMBH (DE) | 2016-04-19 | — | — | US | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20140362334-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-11 | — | — | US | disclosed |
| US-8895117-B2 | Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays | MERCK PATENT GMBH (DE) | 2014-11-25 | — | — | US | disclosed |
| US-20140225035-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140158934-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-05-08 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140362334-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, MAP1LC3C, VCL | PPARD 2373/4885THRB 4838/4885PPARA 2107/4885 |
| US-20140125938-A1 | POLYMERIZABLE COMPOUNDS AND THEIR USE IN LIQUID CRYSTAL MEDIA AND LIQUID CRYSTAL DISPLAYS | LPXN, BPHL, MAP1LC3C | PPARD 2017/4885THRB 4802/4885PPARA 1771/4885 |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | BMP2, IK, EML4 | PPARD 4310/4885THRB 3904/4885PPARA 4624/4885 |
| US-20110261311-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, MAP1LC3C, VCL | PPARD 2373/4885THRB 4838/4885PPARA 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.