Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14189703 | 0.82 | HDAC3 (0.45) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL16092973 | 0.82 | CYP2A6 (0.40) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL15590854 | 0.81 | HDAC3 (0.41) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14378841 | 0.80 | ALDH1A1 (0.44) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL14472433 | 0.77 | HDAC3 (0.38) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15233019 | 0.76 | HDAC1 (0.41) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15590852 | 0.76 | HDAC3 (0.41) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL15605879 | 0.76 | ADH1B (0.50) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| Formic Acid SCHEMBL29231976 | 0.74 | KAT2B (0.40) | PPARGHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27934647 | 0.74 | KDM4E (0.37) | CYP2A6ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102584836-B | Porphyrin cage compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2014-04-16 | — | — | CN | claimed |
| CN-102584836-A | Porphyrin cage compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2012-07-18 | — | — | CN | claimed |
| US-20230110495-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2023-04-13 | — | — | US | disclosed |
| US-11092604-B2 | Glucose sensor molecule | BAXTER INTERNATIONAL INC. (US) | 2021-08-17 | — | — | US | disclosed |
| US-20210052586-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| US-20160178638-A1 | Glucose Sensor Molecule | VANTIVE HEALTH GMBH (CH) | 2016-06-23 | — | — | US | disclosed |
| US-20160178638-A1 | Glucose Sensor Molecule | VANTIVE HEALTH GMBH (CH) | 2016-06-23 | — | — | US | disclosed |
| US-9222941-B2 | Glucose sensor molecules | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-12-29 | — | — | US | disclosed |
| US-9222941-B2 | Glucose sensor molecules | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-12-29 | — | — | US | disclosed |
| US-20140147934-A1 | Glucose sensor molecules | ARES CAPITAL CORPORATION | 2014-05-29 | — | — | US | disclosed |
| US-20130059394-A1 | INDICATOR SYSTEM FOR FIBRE OPTIC SENSOR | LIGHTSHIP MEDICAL LIMITED (GB) | 2013-03-07 | — | — | US | disclosed |
| WO-2012095628-A1 | GLUCOSE SENSOR MOLECULE | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-07-19 | — | — | WO | disclosed |
| CN-102584836-A | Porphyrin cage compound, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2012-07-18 | — | — | CN | disclosed |
| WO-2011101624-A1 | INDICATOR SYSTEM FOR FIBRE OPTIC SENSOR | GLYSURE LTD (GB) | 2011-08-25 | — | — | WO | disclosed |
| EP-1877415-B1 | NEW LABELLING STRATEGIES FOR THE SENSITIVE DETECTION OF ANALYTES | BASECLICK GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1482940-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | Pharmacia Corporation (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-04-29 | — | — | US | disclosed |
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |
| WO-2003028729-A2 | PRODRUGS OF SUBSTITUTED POLYCYCLIC COMPOUNDS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160178638-A1 | Glucose Sensor Molecule | GPR119, GCKR, IRS1 | CYP2A6 4288/4885PPARG 2975/4885HDAC3 4422/4885 |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, LOX | CYP2A6 1089/4885PPARG 959/4885HDAC3 1495/4885 |
| US-20210052586-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, OAT | CYP2A6 1079/4885PPARG 971/4885HDAC3 1503/4885 |
| US-20140147934-A1 | Glucose sensor molecules | GPR119, GCKR, IRS1 | CYP2A6 4230/4885PPARG 2877/4885HDAC3 4315/4885 |
| US-11092604-B2 | Glucose sensor molecule | GPR119, GCKR, IRS1 | CYP2A6 4288/4885PPARG 2975/4885HDAC3 4422/4885 |
| US-20230110495-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | XDH, PNPO, OAT | CYP2A6 1079/4885PPARG 971/4885HDAC3 1503/4885 |
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | TFPI, F2, PLG | CYP2A6 776/4885PPARG 4491/4885HDAC3 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.