SCHEMBL29610302

SCHEMBL29610302

c1ccc(Oc2ccccn2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.52
LTA4H P09960 3/20 0.51
PTGS2 P35354 1/20 0.51
CYP1A2 P05177 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
GPR39 O43194 1/20 0.50
LOX P28300 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
TLR4 O00206 1/20 0.47
TLR2 O60603 1/20 0.47
PDE10A Q9Y233 1/20 0.46
BLM P54132 2/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147539 1.00 LOXL2 (0.52) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL8510667 0.98 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL5443693 0.98 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1
Methyl Alcohol SCHEMBL11157137 0.96 GPR39 (0.51) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL11143982 0.93 PTGS2 (0.57) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL16345487 0.92 LTA4H (0.46) LOXL2LTA4HPTGS2CYP1A2NPC1
Formic Acid SCHEMBL27325993 0.88 TLR4 (0.48) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL7916927 0.88 KDM4E (0.46) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL9135525 0.87 KDM4E (0.56) LOXL2LTA4HPTGS2CYP1A2NPC1
SCHEMBL28001241 0.87 LTA4H (0.50) LOXL2LTA4HPTGS2CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12527214-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-01-13 US disclosed
WO-2025030146-A1 COMPOUNDS CONTAINING ORGANOMETALIC STABILIZED GOLD (III) MACROCYCLES UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-02-06 WO disclosed
US-20240397810-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-11-28 US disclosed
US-20240180886-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE BRISTOL-MYERS SQUIBB COMPANY (US) 2024-06-06 US disclosed
US-11871652-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-09 US disclosed
US-11611042-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-21 US disclosed
US-11495754-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
CN-113105475-B Inhibitors of bruton's tyrosine kinase and methods of use thereof 詹森药业有限公司 2022-09-09 CN disclosed
US-11342516-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11342516-B2 Organic electroluminescent materials and devices ORC3, OCIAD1, ICOSLG LOXL2 149/4885LTA4H 1627/4885PTGS2 4244/4885
US-11611042-B2 Organic electroluminescent materials and devices OCIAD2, JUND, OCIAD1 LOXL2 170/4885LTA4H 603/4885PTGS2 2489/4885
US-11495754-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, EML4 LOXL2 315/4885LTA4H 2910/4885PTGS2 2739/4885
US-20240180886-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE PTPN2, PTPN22, PTPN1 LOXL2 715/4885LTA4H 3665/4885PTGS2 2255/4885
US-11871652-B2 Organic electroluminescent materials and devices IRS1, L1CAM, TLL2 LOXL2 395/4885LTA4H 2410/4885PTGS2 4271/4885
US-20240397810-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ORC3, OCIAD1, ICOSLG LOXL2 149/4885LTA4H 1627/4885PTGS2 4244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.