SCHEMBL14760288

SCHEMBL14760288

CC(=O)[Si](CCl)(C(C)=O)C(C)=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 3/20 0.32
CA4 P22748 2/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
TRPA1 O75762 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14760144 0.71 ALDH1A1 (0.30) ALDH1A1TDP1CA4TSHR
SCHEMBL149763 0.69 ALDH1A1 (0.41) ALDH1A1TDP1TSHRLMNATRPA1
SCHEMBL14760202 0.69 ALDH1A1 (0.41) ALDH1A1TDP1TSHR
SCHEMBL14760124 0.67 ALDH1A1 (0.39) ALDH1A1TDP1LMNATRPA1
SCHEMBL14760296 0.67 ALDH1A1 (0.37) ALDH1A1TDP1LMNATRPA1HSD17B10
SCHEMBL14760277 0.67 TRPA1 (0.44) ALDH1A1TDP1TSHRLMNATRPA1
Acetone SCHEMBL6859386 0.65 LMNA (0.60) ALDH1A1TDP1CA4TSHRLMNA
Acetone SCHEMBL9217023 0.65 LMNA (0.60) ALDH1A1TDP1CA4TSHRLMNA
Acetone SCHEMBL6859109 0.65 LMNA (0.60) ALDH1A1TDP1CA4TSHRLMNA
Acetone SCHEMBL9324675 0.65 LMNA (0.60) ALDH1A1TDP1CA4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US claimed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP claimed
CN-102746426-A Olefin polymerization catalyst, preparation and application thereof PETROCHINA CO LTD 2012-10-24 CN claimed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US disclosed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP disclosed
CN-102746426-A Olefin polymerization catalyst, preparation and application thereof PETROCHINA CO LTD 2012-10-24 CN disclosed