SCHEMBL14760296

SCHEMBL14760296

CC(=O)[Si](CI)(C(C)=O)C(C)=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
CYP2C19 P33261 1/20 0.37
THPO P40225 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14760197 0.78 ALDH1A1 (0.35) ALDH1A1TDP1LMNAKDM4EGMNN
SCHEMBL537436 0.70
SCHEMBL149763 0.69 ALDH1A1 (0.41) ALDH1A1TDP1LMNATHPOHSD17B10
SCHEMBL14760124 0.67 ALDH1A1 (0.39) ALDH1A1TDP1LMNATRPA1
SCHEMBL28089374 0.67 LMNA (0.35) ALDH1A1TDP1LMNAKDM4EGMNN
SCHEMBL14760277 0.67 TRPA1 (0.44) ALDH1A1TDP1LMNATRPA1
SCHEMBL14760288 0.67 ALDH1A1 (0.32) ALDH1A1TDP1LMNAHSD17B10TRPA1
SCHEMBL28576565 0.65 ALDH1A1 (0.37) ALDH1A1TDP1LMNACYP3A4HSD17B10
Iodoacetic Acid SCHEMBL1700764 0.65 FFAR3 (0.54) ALDH1A1TDP1LMNAKDM4EGMNN
Iodoacetic Acid SCHEMBL3163447 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US claimed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP claimed
CN-102746426-A Olefin polymerization catalyst, preparation and application thereof PETROCHINA CO LTD 2012-10-24 CN claimed
US-20130072647-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA COMPANY LIMITED (CN) 2013-03-21 US disclosed
EP-2567986-A1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF Petrochina Company Limited (CN) 2013-03-13 EP disclosed
CN-102746426-A Olefin polymerization catalyst, preparation and application thereof PETROCHINA CO LTD 2012-10-24 CN disclosed