SCHEMBL1476031

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3797323	0.89	MAPKAPK5 (0.46)	MAPKAPK5EGFRAURKAKDRFLT3
	SCHEMBL1475644	0.87	MAPKAPK5 (0.58)	MAPKAPK5EGFRKDRFGFR1BRAF
	SCHEMBL2220573	0.86	MAPKAPK5 (0.73)	MAPKAPK5EGFRFLT3SYK
	SCHEMBL3801252	0.81	MAPKAPK5 (0.47)	MAPKAPK5EGFRKDRFGFR1BRAF
	SCHEMBL2220311	0.80	MAPKAPK5 (0.74)	MAPKAPK5EGFRAURKAKDRPRKAB2
	SCHEMBL1477789	0.80	MAPKAPK5 (0.61)	MAPKAPK5FLT3SYK
	SCHEMBL2217450	0.78	MAPKAPK5 (0.62)	MAPKAPK5FYNAURKASYK
	SCHEMBL1476377	0.78	MAPKAPK5 (0.48)	MAPKAPK5EGFRAURKAPRKAB2PRKAG1
	SCHEMBL3803496	0.76	MAPKAPK5 (0.60)	MAPKAPK5EGFRSYK
	SCHEMBL1477728	0.75	MAPKAPK5 (0.55)	MAPKAPK5EGFRAURKAKDRFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.