SCHEMBL14760883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15653444	0.82	AKR1B1 (0.41)	TAAR1CFDAKR1B1GAACYP1A2
	SCHEMBL15654975	0.82	TAAR1 (0.39)	TAAR1CFDAKR1B1GAACYP1A2
	SCHEMBL15654413	0.80	TAAR1 (0.38)	TAAR1CFDAKR1B1GAACYP1A2
	SCHEMBL9770	0.78	TAAR1 (0.50)	TAAR1AKR1B1GAACYP1A2CYP3A4
	SCHEMBL23326430	0.78	—	—
	SCHEMBL29861568	0.78	—	—
	SCHEMBL11029873	0.75	TAAR1 (0.48)	TAAR1AKR1B1GAACYP1A2CYP3A4
	SCHEMBL29713144	0.72	TAAR1 (0.61)	TAAR1GAACYP1A2CYP3A4SMN1; SMN2
	SCHEMBL4706	0.72	TAAR1 (0.61)	TAAR1GAACYP1A2CYP3A4SMN1; SMN2
	SCHEMBL16952901	0.72	PNMT (0.56)	TAAR1CYP1A2CYP3A4CYP2D6NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.