SCHEMBL9770

SCHEMBL9770

Clc1cccc(Cl)c1CBr

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.50
AKR1B1 P15121 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2A6 P11509 1/20 0.43
LMNA P02545 2/20 0.42
TSHR P16473 1/20 0.42
GAA P10253 1/20 0.40
ALDH1A1 P00352 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
GLA P06280 1/20 0.39
HTT P42858 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
CYP2A13 Q16696 1/20 0.39
PNMT P11086 1/20 0.39
DPP4 P27487 1/20 0.38
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11029873 0.97 TAAR1 (0.48) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL29649325 0.85 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL1294517 0.85 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL695878 0.85 TAAR1 (0.43) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL6358890 0.83 TAAR1 (0.41) TAAR1AKR1B1SMN1; SMN2LMNAGAA
SCHEMBL1627393 0.83 TAAR1 (0.41) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL29713144 0.83 TAAR1 (0.61) TAAR1SMN1; SMN2CYP1A2LMNAGAA
SCHEMBL31454412 0.83 TAAR1 (0.41) TAAR1AKR1B1SMN1; SMN2CYP1A2CYP2A6
SCHEMBL4706 0.83 TAAR1 (0.61) TAAR1SMN1; SMN2CYP1A2LMNAGAA
SCHEMBL7828184 0.82 TDP1 (0.48) TAAR1AKR1B1SMN1; SMN2LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4640672-A1 ETHYLENEDIAMINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu Protelight Pharmaceutical & Biotechnology Co., Ltd. (CN) 2025-10-29 EP claimed
CN-115784972-B Ethylenediamine derivative and preparation method and application thereof 江苏普莱医药生物技术有限公司 2025-04-11 CN claimed
WO-2024130690-A1 ETHYLENEDIAMINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 江苏普莱医药生物技术有限公司 2024-06-27 WO claimed
CN-115784972-A Ethylene diamine derivative and preparation method and application thereof 江苏普莱医药生物技术有限公司 2023-03-14 CN claimed
EP-4013398-A1 AN IMPROVED PROCESS FOR PREPARATION OF VILANTEROL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Melody Healthcare Pvt. Ltd. (IN) 2022-06-22 EP claimed
CN-114409524-A Preparation method of 2, 6-dichlorophenylacetic acid 上海柏狮生物科技有限公司 2022-04-29 CN claimed
WO-2021033198-A1 AN IMPROVED PROCESS FOR PREPARATION OF VILANTEROL OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Melody Healthcare Pvt. Ltd (IN) 2021-02-25 WO claimed
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds SHELL OIL COMPANY 2001-11-08 US claimed
US-12570609-B2 Tricyclic sulfones as ROR gamma modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2026-03-10 US disclosed
US-20260022094-A1 Compounds for the Treatment of Neurodegenerative Diseases CELGENE CORPORATION (US) 2026-01-22 US disclosed
EP-4640672-A1 ETHYLENEDIAMINE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu Protelight Pharmaceutical & Biotechnology Co., Ltd. (CN) 2025-10-29 EP disclosed
US-12410142-B2 Substituted imidazole salt compounds, preparation method thereof, pharmaceutical composition thereof and application thereof XIAMEN VIVOHEALTHS TECHNOLOGY CO., LTD. (CN) 2025-09-09 US disclosed
US-20250228865-A1 COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME SANOFI US SERVICES INC. (US) 2025-07-17 US disclosed
US-12357612-B2 Prophylactic or therapeutic agent for cancer TOHOKU UNIVERSITY (JP) 2025-07-15 US disclosed
US-4241079-A ANTHELMINTICS AND FUNGICIDES ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4172834-A ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS STERLING DRUG INC. (US) 1979-10-30 US disclosed
US-4170650-A Oxopiperazinium salts, their preparation and their use THE DOW CHEMICAL COMPANY (US) 1979-10-09 US disclosed
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed
US-4062864-A ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1977-12-13 US disclosed
US-3959309-A ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE STERLING DRUG INC. (US) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570609-B2 Tricyclic sulfones as ROR gamma modulators RORC, RORB, RORA TAAR1 272/4885AKR1B1 1347/4885SMN1; SMN2 1107/4885
US-12357612-B2 Prophylactic or therapeutic agent for cancer TSG101, FABP2, BRCA1 TAAR1 4550/4885AKR1B1 579/4885SMN1; SMN2 4272/4885
US-20260022094-A1 Compounds for the Treatment of Neurodegenerative Diseases S1PR5, CLN6, S1PR1 TAAR1 172/4885AKR1B1 1794/4885SMN1; SMN2 37/4885
US-20250228865-A1 COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME UPF1, NUDT21, RNGTT TAAR1 3612/4885AKR1B1 2484/4885SMN1; SMN2 1143/4885
US-12410142-B2 Substituted imidazole salt compounds, preparation method thereof, pharmaceutical composition thereof and application thereof ALDOA, IDE, ACAT1 TAAR1 2711/4885AKR1B1 29/4885SMN1; SMN2 433/4885
US-20010039349-A1 Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds AHR, PAH, HRH3 TAAR1 1113/4885AKR1B1 2216/4885SMN1; SMN2 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.