SCHEMBL4706

SCHEMBL4706

Fc1cccc(Cl)c1CBr

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.61
GAA P10253 1/20 0.57
HTT P42858 2/20 0.49
BACE1 P56817 1/20 0.49
KDM4E B2RXH2 2/20 0.47
CYP2A13 Q16696 1/20 0.47
NPSR1 Q6W5P4 2/20 0.46
ATM Q13315 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.44
DAO P14920 1/20 0.44
LMNA P02545 1/20 0.44
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29713144 1.00 TAAR1 (0.61) TAAR1GAAHTTBACE1KDM4E
SCHEMBL2919993 0.98 TAAR1 (0.59) TAAR1GAAHTTBACE1KDM4E
SCHEMBL11030444 0.98 TAAR1 (0.59) TAAR1GAAHTTBACE1KDM4E
Benzyl Bromide SCHEMBL634338 0.89 LMNA (0.51) TAAR1GAAHTTBACE1KDM4E
SCHEMBL121801 0.83 TAAR1 (0.43) TAAR1GAAHTTBACE1KDM4E
SCHEMBL9770 0.83 TAAR1 (0.50) TAAR1GAAHTTCYP2A13NPSR1
SCHEMBL27737807 0.83 TAAR1 (0.68) TAAR1GAAHTTBACE1KDM4E
Hydrochloric Acid SCHEMBL29184016 0.80 TAAR1 (0.41) TAAR1GAAHTTBACE1KDM4E
SCHEMBL11029574 0.80 TAAR1 (0.41) TAAR1GAAHTTBACE1KDM4E
SCHEMBL11029873 0.80 TAAR1 (0.48) TAAR1GAAHTTCYP2A13NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins AVILAR THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-12410142-B2 Substituted imidazole salt compounds, preparation method thereof, pharmaceutical composition thereof and application thereof XIAMEN VIVOHEALTHS TECHNOLOGY CO., LTD. (CN) 2025-09-09 US disclosed
EP-4536642-A1 HETEROCYCLIC COMPOUNDS AS PI3KA INHIBITORS Synnovation Therapeutics, Inc. (US) 2025-04-16 EP disclosed
CN-115151304-B Small molecule interferon gene stimulating factor (STING) antagonists 库拉德夫制药私人有限公司 2025-02-11 CN disclosed
CN-118693282-B Secondary battery and preparation method and application thereof 蜂巢能源科技股份有限公司 2024-12-03 CN disclosed
US-20240360143-A1 [1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-7(8H)-ONE AS MITOCHONDRIAL PYRUVATE CARRIER INHIBITORS FOR USE IN THE TREATMENT OF CANCER UNIVERSITE DE GENEVE (CH) 2024-10-31 US disclosed
CN-111132972-B Small molecule modulators of human STING 克拉德夫制药有限公司 2024-07-12 CN disclosed
EP-3608312-B1 SUBSTITUTED IMIDAZOLE SALT COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF XIAMEN VIVOHEALTHS TECH CO LTD (CN) 2024-06-26 EP disclosed
EP-3608312-B1 SUBSTITUTED IMIDAZOLE SALT COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF XIAMEN VIVOHEALTHS TECH CO LTD (CN) 2024-06-26 EP disclosed
WO-2004011443-A1 PYRIMIDYL SULPHONE AMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2004-02-05 WO disclosed
WO-2004009091-A1 PURINE DERIVATIVES AS LIVER X RECEPTOR AGONISTS GLAXO GROUP LIMITED (GB) 2004-01-29 WO disclosed
EP-1366026-A2 PYRIMIDINE COMPOUNDS AND THEIR USE SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2003-12-03 EP disclosed
CN-1443164-A Pyrrolidine derivatives as metalloprotease inhibitors HOFFMANN LA ROCHE (CH) 2003-09-17 CN disclosed
WO-2002024663-A2 PYRIMIDINE COMPOUNDS AND THEIR USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-28 WO disclosed
US-5175314-A Plant growth controller E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US disclosed
US-4946858-A ANTIDIABETIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1990-08-07 US disclosed
US-4900739-A ANTIDIABETIC AGENTS AMERICAN HOME PRODUCTS CORP. (US) 1990-02-13 US disclosed
US-4900826-A REACTING METAL SALT OF N6-SUBSTITUTED ADENINE WITH BENZYL HALIDE USING ETHER PHASE TRANSFER CATALYST KOHJIN CO., LTD. (JP) 1990-02-13 US disclosed
US-3953597-A POULTRY FEEDS INTERNATIONAL MINERALS & CHEMICAL CORPORATION (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360143-A1 [1,2,4]TRIAZOLO[4,3-A]PYRIMIDIN-7(8H)-ONE AS MITOCHONDRIAL PYRUVATE CARRIER INHIBITORS FOR USE IN THE TREATMENT OF CANCER MPC2, PC, SLC25A1 TAAR1 4483/4885GAA 1801/4885HTT 2321/4885
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins IGF2R, M6PR, MSR1 TAAR1 387/4885GAA 1965/4885HTT 4036/4885
US-12410142-B2 Substituted imidazole salt compounds, preparation method thereof, pharmaceutical composition thereof and application thereof ALDOA, IDE, ACAT1 TAAR1 2711/4885GAA 15/4885HTT 428/4885
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 TAAR1 2336/4885GAA 373/4885HTT 1602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.