SCHEMBL14764381

SCHEMBL14764381

COc1ccc(-c2oc3cccc(O)c3c(=O)c2O)cc1O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 3/20 0.76
CYP1A2 P05177 3/20 0.76
CYP1B1 Q16678 3/20 0.76
XDH P47989 2/20 0.74
DPP4 P27487 1/20 0.74
MKNK2 Q9HBH9 1/20 0.70
MEN1 O00255 5/20 0.63
KMT2A Q03164 5/20 0.63
MAPT P10636 5/20 0.63
TUBB4A P04350 4/20 0.63
TUBB P07437 4/20 0.63
TUBA3C P0DPH7 4/20 0.63
TUBA1B P68363 4/20 0.63
TUBA4A P68366 4/20 0.63
TUBB4B P68371 4/20 0.63
TUBB3 Q13509 4/20 0.63
TUBB2A Q13885 4/20 0.63
TUBB8 Q3ZCM7 4/20 0.63
TUBA3E Q6PEY2 4/20 0.63
TUBA1A Q71U36 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14764339 0.90 MEN1 (0.76) CYP1A1CYP1A2CYP1B1XDHDPP4
Tamarixetin SCHEMBL892776 0.86 CYP1A2 (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
Tamarixetin SCHEMBL29750609 0.86 CYP1A2 (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
Tamarixetin SCHEMBL30255798 0.86 CYP1A2 (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
Ombuine SCHEMBL1252211 0.85 XDH (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
Ombuine SCHEMBL29475881 0.85 XDH (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
Ombuine SCHEMBL31516400 0.85 XDH (1.00) CYP1A1CYP1A2CYP1B1XDHDPP4
SCHEMBL7660030 0.85 NOX4 (0.76) CYP1A1CYP1A2CYP1B1XDHDPP4
SCHEMBL16237902 0.85 KDM4E (0.83) CYP1A1CYP1A2CYP1B1XDHDPP4
SCHEMBL18676308 0.84 MEN1 (0.72) CYP1A1CYP1A2CYP1B1XDHDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013034119-A1 4-METHYLCATECHOL DERIVATIVES UND USE THEREOF Thanares GmbH (DE) 2013-03-14 WO disclosed