Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14765662 | 0.94 | KDM1A (0.36) | FPR2FFAR4KDM1AGABRA1GABRB2 | |
| SCHEMBL14765685 | 0.93 | FPR2 (0.36) | SCN9AFPR2RAB9AFFAR4RARA | |
| SCHEMBL14765837 | 0.91 | FPR2 (0.39) | SCN9AFPR2RAB9AFFAR4RARA | |
| SCHEMBL14765848 | 0.90 | CNR2 (0.35) | CNR2SCN9ARAB9AFFAR4CNR1 | |
| SCHEMBL12733939 | 0.89 | HTR1A (0.32) | FPR2KDM1A | |
| SCHEMBL14766774 | 0.89 | FFAR1 (0.39) | CNR2SCN9AFFAR4KDM1APPARG | |
| SCHEMBL14765804 | 0.89 | FFAR4 (0.36) | CNR2RAB9AFFAR4CNR1RARA | |
| SCHEMBL14767103 | 0.88 | FFAR1 (0.38) | CNR2SCN9AFFAR4RARARARB | |
| SCHEMBL14765920 | 0.87 | NAAA (0.35) | CNR2RAB9AFFAR4CNR1KDM1A | |
| SCHEMBL14766954 | 0.87 | GABRA1 (0.35) | CNR2SCN9AFFAR4CNR1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394294-B2 | Four-ring liquid crystal compound having lateral fluorine, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |