Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21095839 | 0.92 | AR (0.39) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL12889534 | 0.87 | TRPV4 (0.33) | ALDH1A1GLAGAAHPGDATM | |
| SCHEMBL21095946 | 0.87 | PDE9A (0.35) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL19557557 | 0.86 | ADORA1 (0.37) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL14768649 | 0.86 | PDE9A (0.37) | ARALDH1A1GLAGAAHPGD | |
| SCHEMBL21498301 | 0.86 | TRPV4 (0.38) | ARTRPV4MAPT | |
| SCHEMBL10018744 | 0.86 | CYP11B1 (0.38) | ARCYP11B1CYP11B2KIF11MAPT | |
| SCHEMBL13447449 | 0.85 | CYP11B1 (0.34) | ARCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL12929135 | 0.85 | CYP11B1 (0.34) | ARCYP11B1CYP11B2MAPTCYP1A2 | |
| SCHEMBL2741546 | 0.85 | CYP11B1 (0.34) | ARCYP11B1CYP11B2MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982149-B2 | Chiral compounds | MERCK PATENT GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10450509-B2 | Liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-20170226422-A1 | POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| EP-3124573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | Merck Patent GmbH (DE) | 2017-02-01 | — | — | EP | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-9120969-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2015-09-01 | — | — | US | disclosed |
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-05-14 | — | — | US | disclosed |
| US-20140225035-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140158934-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20140077130-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| EP-2568032-A2 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2013-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10982149-B2 | Chiral compounds | FANCI, COL1A1, LCP1 | AR 1029/4885ALDH1A1 371/4885GLA 1289/4885 |
| US-10450509-B2 | Liquid crystal medium and liquid display | NEFM, CRY1, BMP2 | AR 4261/4885ALDH1A1 3890/4885GLA 289/4885 |
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | CCND2, CFD, CRY1 | AR 3566/4885ALDH1A1 3890/4885GLA 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.