Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14818106 | 0.94 | MAOA (0.38) | EGFRMAOAACHECA1CA2 | |
| SCHEMBL2417713 | 0.88 | CYP3A4 (0.33) | MAOACA1CA2ALDH1A1MAPT | |
| SCHEMBL12322167 | 0.66 | TGM2 (0.40) | CA1CA2MAPTMEN1KMT2A | |
| SCHEMBL4400137 | 0.62 | MAOB (0.50) | MAOAACHECA1CA2PTGS2 | |
| SCHEMBL19437875 | 0.61 | ACHE (0.53) | EGFRACHECA1CA2ALDH1A1 | |
| SCHEMBL69624 | 0.61 | MAOB (0.59) | CA1CA2ALDH1A1LMNATP53 | |
| SCHEMBL13008679 | 0.60 | KDM4E (0.50) | CA2ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24285723 | 0.60 | ACHE (0.47) | EGFRACHECA1CA2ALDH1A1 | |
| SCHEMBL1599771 | 0.59 | GAA (0.56) | CA2ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL11702085 | 0.59 | PKM (0.53) | CA2ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |