SCHEMBL1476777

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1475003	0.88	KDM4E (0.41)	ALDH1A1KDM4E
	SCHEMBL1475371	0.82	ALDH1A1 (0.37)	F2F10ALDH1A1RXFP1SCN3A
	SCHEMBL5898600	0.80	GPR119 (0.40)	F2F10ALDH1A1RXFP1SCN3A
	SCHEMBL1477074	0.80	SIGMAR1 (0.43)	ALDH1A1KDM4EMAPK1NPSR1
	SCHEMBL1476417	0.76	CHRNB4 (0.42)	KCNH2
	SCHEMBL1475264	0.73	SIGMAR1 (0.45)	ALDH1A1KDM4EMAPK1NPSR1
	SCHEMBL1476076	0.72	SIGMAR1 (0.41)	ALDH1A1KDM4EMAPK1KMT2A
	SCHEMBL1475515	0.72	CD274 (0.43)	ALDH1A1RXFP1KDM4EMAPK1NPSR1
	SCHEMBL1475386	0.72	PDCD1 (0.47)	ALDH1A1RXFP1MAPK1NPSR1KMT2A
	SCHEMBL1475282	0.72	CACNA1G (0.42)	F2F10ALDH1A1GPR119KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.