Sugi Predict

Sugi Predict / Compounds / SCHEMBL8249778

SCHEMBL8249778

SCHEMBL8249778

COC(=O)[C@@H](N)CC(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC15A1 P46059 2/20 0.57
▸ ALDH1A1 P00352 3/20 0.53
▸ MAPK1 P28482 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ LTA4H P09960 3/20 0.50
▸ ABCB1 P08183 2/20 0.49
▸ MMP9 P14780 1/20 0.46
▸ SLC1A3 P43003 1/20 0.45
▸ SLC1A1 P43005 1/20 0.45
▸ SLC6A2 P23975 1/20 0.45
▸ SLC6A3 Q01959 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ CDC25B P30305 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30916032 1.00 SLC15A1 (0.57) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL7470329 1.00 SLC15A1 (0.57) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
Hydrochloric Acid SCHEMBL20899707 0.98 SLC15A1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
Hydrochloric Acid SCHEMBL20899708 0.98 SLC15A1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
Hydrochloric Acid SCHEMBL29828972 0.98 SLC15A1 (0.56) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL589203 0.89 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL589202 0.89 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL1264374 0.89 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL32681189 0.89 SLC15A1 (0.61) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H
SCHEMBL304329 0.88 ABCB1 (0.52) SLC15A1ALDH1A1MAPK1L3MBTL1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3700578-B1 SYSTEMS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC (US) 2025-12-03 — — EP disclosed
US-12303570-B2 Compositions and methods for assessing eye vasculature MEDIBEACON INC. (US) 2025-05-20 — — US disclosed
US-11834515-B2 Macrocyclic compounds as proteasome inhibitors CORNELL UNIVERSITY (US) 2023-12-05 — — US disclosed
US-11834515-B2 Macrocyclic compounds as proteasome inhibitors CORNELL UNIVERSITY (US) 2023-12-05 — — US disclosed
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SHANGHAI LUMOSA THERAPEUTICS CO LTD (CN) 2023-10-05 — — US disclosed
US-11708336-B2 Anodic oxidation of 5-aminouracil MEDIBEACON INC. (US) 2023-07-25 — — US disclosed
US-20230173111-A1 COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC. 2023-06-08 — — US disclosed
US-20230158175-A1 METHODS FOR RENAL FUNCTION DETERMINATION MEDIBEACON INC. 2023-05-25 — — US disclosed
WO-2023083291-A1 DERIVATIVE OF ASPARTIC ACID AND USE THEREOF IN TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS 深圳利沃生物医药科技有限公司 2023-05-19 — — WO disclosed
US-20230132384-A9 COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE MEDIBEACON INC. 2023-04-27 — — US disclosed
US-11602570-B2 Compositions and systems for renal function determination MEDIBEACON INC. (US) 2023-03-14 — — US disclosed
US-11590244-B2 Methods for renal function determination MEDIBEACON INC. (US) 2023-02-28 — — US disclosed
EP-4041235-A1 ANODIC OXIDATION OF 5-AMINOURACIL Medibeacon Inc. (US) 2022-08-17 — — EP disclosed
WO-2019075259-A1 MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS CORNELL UNIVERSITY (US) 2019-04-18 — — WO disclosed
US-20040082496-A1 ACE-2 modulating compounds and methods of use thereof MILLENNIUM PHARMACEUTICALS, INC. 2004-04-29 — — US disclosed
US-20040082496-A1 ACE-2 modulating compounds and methods of use thereof MILLENNIUM PHARMACEUTICALS, INC. 2004-04-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040082496-A1 ACE-2 modulating compounds and methods of use thereof ACE, ACE2, AGTR2 SLC15A1 3442/4885ALDH1A1 1305/4885MAPK1 1850/4885
US-11602570-B2 Compositions and systems for renal function determination GLS, ATP6V1B1, REN SLC15A1 218/4885ALDH1A1 3528/4885MAPK1 3824/4885
US-11708336-B2 Anodic oxidation of 5-aminouracil DPYD, DHODH, AASDHPPT SLC15A1 1127/4885ALDH1A1 297/4885MAPK1 2286/4885
US-20230132384-A9 COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE LIPG, FLT4, FABP3 SLC15A1 2301/4885ALDH1A1 1933/4885MAPK1 4862/4885
US-20230173111-A1 COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION GLS, ATP6V1B1, REN SLC15A1 218/4885ALDH1A1 3528/4885MAPK1 3824/4885
US-11834515-B2 Macrocyclic compounds as proteasome inhibitors PSMB5, PSMB1, PSMB3 SLC15A1 4075/4885ALDH1A1 4081/4885MAPK1 2110/4885
US-20230312644-A1 COMPOUNDS HAVING TRIPLE ACTIVITIES OF THROMBOLYSIS, ANTITHROMBOTIC AND RADICAL SCAVENGING SERPINC1, PLAT, F2 SLC15A1 3690/4885ALDH1A1 1478/4885MAPK1 2243/4885
US-11590244-B2 Methods for renal function determination GLS, REN, ATP6V1B1 SLC15A1 207/4885ALDH1A1 1132/4885MAPK1 1929/4885
US-20230158175-A1 METHODS FOR RENAL FUNCTION DETERMINATION GLS, SHBG, OGFR SLC15A1 253/4885ALDH1A1 1776/4885MAPK1 2580/4885
US-12303570-B2 Compositions and methods for assessing eye vasculature LIPG, FLT4, FABP3 SLC15A1 2301/4885ALDH1A1 1933/4885MAPK1 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.