Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599620 | 0.89 | KDM4C (0.50) | KDM4CMAPTLMNATSHRMAPK1 | |
| SCHEMBL10206259 | 0.89 | HSP90AA1 (0.45) | KDM4CMAPTGAALMNATSHR | |
| SCHEMBL2139058 | 0.87 | KCNN3 (0.49) | MAPTGAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10206291 | 0.83 | ALDH1A1 (0.43) | MAPTGAAMAPK1TDP1L3MBTL1 | |
| SCHEMBL12182375 | 0.83 | KDM4C (0.39) | KDM4CMAPTGAATSHRTDP1 | |
| SCHEMBL2136399 | 0.81 | ABL1 (0.46) | MAPTGAALMNAHSP90AA1HSP90B1 | |
| SCHEMBL2137055 | 0.80 | HDAC8 (0.46) | MAPTLMNAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL2137867 | 0.78 | SMN1; SMN2 (0.41) | MAPTGAALMNAMAPK1TDP1 | |
| SCHEMBL2135922 | 0.78 | KDM4C (0.52) | KDM4CMAPTLMNATSHRALDH1A1 | |
| SCHEMBL2132573 | 0.78 | CA1 (0.45) | MAPTGAAL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065757-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065757-A1 | CHEMICAL COMPOUNDS | HPD, PPOX, PIN1 | KDM4C 3820/4885MAPT 2450/4885GAA 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.