Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL14762029 | 0.87 | DPP8 (0.34) | — | |
| SCHEMBL14769248 | 0.84 | FKBP1A (0.32) | — | |
| SCHEMBL15341682 | 0.83 | DUT (0.32) | DUT | |
| SCHEMBL15570492 | 0.75 | DUT (0.31) | DUT | |
| SCHEMBL12381955 | 0.75 | HRH3 (0.33) | DUT | |
| Hydrochloric Acid SCHEMBL14762100 | 0.74 | GNAO1 (0.34) | DUT | |
| Trifluoroacetic Acid SCHEMBL14761998 | 0.73 | DPP8 (0.35) | — | |
| SCHEMBL31607863 | 0.73 | DUT (0.32) | DUT | |
| SCHEMBL7790340 | 0.72 | DUT (0.35) | DUT | |
| SCHEMBL20573109 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648099-B2 | 3-pyridine carboxylic acid hydrazides | HOFFMANN-LA ROCHE INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-20130065876-A1 | 3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065876-A1 | 3-PYRIDINE CARBOXYLIC ACID HYDRAZIDES | HMGCR, HCAR3, HCAR1 | DUT 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.