Ipratropium

Ipratropium

SCHEMBL1476940

CC(C)[N+]1(C)C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2.O.[Br-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM3

The experimentally established mechanism targets of Ipratropium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 known ✓ P20309 5/20 1.00
CHRM2 P08172 7/20 1.00
CHRM5 P08912 6/20 1.00
CHRM1 P11229 5/20 1.00
CHRM4 P08173 4/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
SMN1; SMN2 Q16637 2/20 1.00
TSHR P16473 2/20 0.95
BLM P54132 5/20 0.79
PABPC1 P11940 1/20 0.75
CYP2C19 P33261 1/20 0.73
CYP3A4 P08684 1/20 0.62
CYP2C9 P11712 1/20 0.62
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62
KDM4E B2RXH2 1/20 0.61
LMNA P02545 1/20 0.61
POLB P06746 1/20 0.61
ADRA2C P18825 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ipratropium SCHEMBL22077027 1.00 CHRM2 (1.00) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL820105 1.00 CHRM2 (1.00) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL1476937 1.00 CHRM2 (1.00) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL1476943 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL29152427 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3136875 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL16762661 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3852 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL3854 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4
Ipratropium SCHEMBL6854302 0.99 CHRM2 (0.98) CHRM2CHRM5CHRM1CHRM3CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260077140-A1 METERED DOSE INHALER FOR IPRATROPIUM BROMIDE SOLUTION GLENMARK PHARMACEUTICALS LTD (IN) 2026-03-19 US claimed
US-12502489-B1 Metered dose inhaler for ipratropium bromide solution GLENMARK PHARMACEUTICALS LIMITED (IN) 2025-12-23 US claimed
EP-3624771-B1 METHOD OF MAINTAINING A WATER LEVEL IN A PRESSURIZED AEROSOL CANISTER. KINDEVA DRUG DELIVERY LP (US) 2023-11-15 EP claimed
CN-113820404-B UPLC analysis method of ipratropium bromide aerosol 山东达因海洋生物制药股份有限公司 2023-04-25 CN claimed
CN-113943286-B Preparation method of choline receptor antagonist 上海方予健康医药科技有限公司 2023-04-18 CN claimed
CN-112438966-B Medical quantitative inhalation aerosol 四川普锐特药业有限公司 2022-08-26 CN claimed
EP-1809243-B2 AEROSOL SUSPENSION FORMULATIONS CONTAINING TG 227 EA AS A PROPELLANT BOEHRINGER INGELHEIM INT (DE) 2022-06-08 EP claimed
CN-110845492-B Ipratropium bromide monohydrate 鲁南制药集团股份有限公司 2022-05-13 CN claimed
US-20220040086-A1 FORMULATION AND AEROSOL CANISTERS, INHALERS, AND THE LIKE CONTAINING THE FORMULATION JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2022-02-10 US claimed
CN-113943286-A Preparation method of choline receptor antagonist 上海方予健康医药科技有限公司 2022-01-18 CN claimed
EP-1809243-A2 AEROSOL SUSPENSION FORMULATIONS CONTAINING TG 227 EA OR TG 134 A AS A PROPELLANT BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-07-25 EP claimed
CN-1984642-A Aerosol suspension formulations containing TG 227 ea or TG 134 a as a propellant BOEHRINGER INGELHEIM INT (DE) 2007-06-20 CN claimed
US-20070041911-A1 HFC SOLUTION FORMULATIONS CONTAINING SALBUTAMOL HYDROCHLORIDE OR SALBUTAMOL CITRATE SCHMIDT FRIEDRICH 2007-02-22 US claimed
WO-2006002840-A2 AEROSOL SUSPENSION FORMULATIONS CONTAINING TG 227 EA OR TG 134 A AS A PROPELLANT BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-12 WO claimed
US-6983743-B2 Stainless steel canister for propellant-driven metering aerosols BOEHRINGER INGELHEIM PHARMA KG (DE) 2006-01-10 US claimed
US-20060002863-A1 Aerosol suspension formulations containing TG 227 ea or TG 134 a as propellant BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2006-01-05 US claimed
EP-1608336-A2 FORMULATION FOR A METERED DOSE INHALER USING HYDRO-FLUORO-ALKANES AS PROPELLANTS BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 2005-12-28 EP claimed
US-20040211411-A1 Stainless steel canister for propellant-driven metering aerosols BOEHRINGER INGELHEIM PHARMA KG (DE) 2004-10-28 US claimed
WO-2004084858-A2 FORMULATION FOR A METERED DOSE INHALER USING HYDRO-FLUORO-ALKANES AS PROPELLANTS BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 2004-10-07 WO claimed
US-20040184994-A1 Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 2004-09-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220040086-A1 FORMULATION AND AEROSOL CANISTERS, INHALERS, AND THE LIKE CONTAINING THE FORMULATION MCOLN3, SYMPK, ADRB2 CHRM3 20/4885CHRM2 47/4885CHRM5 30/4885
US-20260077140-A1 METERED DOSE INHALER FOR IPRATROPIUM BROMIDE SOLUTION ADRB2, CHRM2, CHRNB1 CHRM3 5/4885CHRM2 2/4885CHRM5 8/4885
US-20070041911-A1 HFC SOLUTION FORMULATIONS CONTAINING SALBUTAMOL HYDROCHLORIDE OR SALBUTAMOL CITRATE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, MYOC, OTC CHRM3 17/4885CHRM2 154/4885CHRM5 100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.