Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17228757 | 0.85 | KDM4E (0.41) | KDM4EATML3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL14770586 | 0.83 | ALOX5 (0.39) | KDM4EATML3MBTL1DUSP3ALOX5 | |
| SCHEMBL21583622 | 0.82 | PRKDC (0.45) | KDM4EDUSP3ALDH1A1PRKDC | |
| SCHEMBL5028226 | 0.82 | ALOX5 (0.41) | KDM4EATML3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL17805947 | 0.80 | ALDH1A1 (0.41) | KDM4EATML3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL21397041 | 0.79 | CYP11B2 (0.39) | KDM4EATML3MBTL1DUSP3ALDH1A1 | |
| SCHEMBL5028253 | 0.79 | KDM4E (0.45) | KDM4EATML3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL5030179 | 0.79 | ALOX5 (0.36) | KDM4EATML3MBTL1ALOX5ALDH1A1 | |
| SCHEMBL14770597 | 0.79 | KDM4E (0.35) | KDM4EATML3MBTL1DUSP3ALOX5 | |
| SCHEMBL14770585 | 0.78 | ALOX5 (0.35) | ALOX5PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | KDM4E 1763/4885ATM 1105/4885L3MBTL1 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.