Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PTPRF | P10586 | 9/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 9/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14770633 | 0.98 | PRKDC (0.36) | PRKDCKDM4EATML3MBTL1PLA2G2A | |
| SCHEMBL14770629 | 0.92 | KDM4E (0.38) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL14770715 | 0.91 | L3MBTL1 (0.37) | PRKDCKDM4EATML3MBTL1PLA2G2A | |
| SCHEMBL14770636 | 0.91 | CASP3 (0.36) | PRKDCKDM4EATML3MBTL1PLA2G2A | |
| SCHEMBL14770645 | 0.91 | KMT2A (0.37) | PRKDCKDM4EATML3MBTL1PLA2G2A | |
| SCHEMBL10041340 | 0.91 | KDM4E (0.38) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL14867943 | 0.90 | KMT2A (0.38) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL14770569 | 0.88 | KDM4E (0.38) | KDM4EATML3MBTL1PLA2G2APLA2G4A | |
| SCHEMBL14770574 | 0.87 | KDM4E (0.43) | KDM4EATML3MBTL1PTPRFPTPN2 | |
| SCHEMBL14733877 | 0.86 | PLA2G2A (0.39) | PRKDCKDM4EATML3MBTL1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-9604972-B2 | Nitrogen-containing heteroaromatic ring compound | IDEMITSU KOSAN CO., LTD. (JP) | 2017-03-28 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | IDEMITSU KOSAN CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130062597-A1 | NITROGEN-CONTAINING HETEROAROMATIC RING COMPOUND | TDO2, AHR, NOC2L | PRKDC 3941/4885KDM4E 1763/4885ATM 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.