Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857630 | 0.82 | HDAC8 (0.38) | GRM5HDAC8ACHEKMT2AEGFR | |
| SCHEMBL29524972 | 0.78 | GRM5 (0.41) | GRM5HDAC8EGFRGABRA1GABRA5 | |
| SCHEMBL1476059 | 0.78 | GRM5 (0.41) | GRM5HDAC8EGFRGABRA1GABRA5 | |
| SCHEMBL5718769 | 0.78 | ALDH1A1 (0.40) | HDAC8ACHETSHR | |
| SCHEMBL532567 | 0.77 | EGLN2 (0.48) | GRM5HDAC8ACHEMEN1KMT2A | |
| SCHEMBL3279463 | 0.77 | GRM5 (0.44) | GRM5ACHEMEN1KMT2AATM | |
| SCHEMBL16951938 | 0.77 | GRM5 (0.44) | GRM5ACHEMEN1KMT2AATM | |
| SCHEMBL9996657 | 0.77 | GRM5 (0.44) | GRM5ACHEMEN1KMT2AATM | |
| SCHEMBL7996636 | 0.76 | GRM5 (0.50) | GRM5ACHEMEN1KMT2AATM | |
| SCHEMBL3841101 | 0.74 | HDAC8 (0.34) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9107959-B2 | Method for site-specific polyvalent display on polymers | NEW YORK UNIVERSITY (US) | 2015-08-18 | — | — | US | claimed |
| US-20140113862-A1 | METHOD FOR SITE-SPECIFIC POLYVALENT DISPLAY ON POLYMERS | NEW YORK UNIVERSITY | 2014-04-24 | — | — | US | claimed |
| US-8524663-B2 | Method for site-specific polyvalent display on polymers | NEW YORK UNIVERSITY (US) | 2013-09-03 | — | — | US | claimed |
| WO-2025034034-A1 | NOVEL COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER OR TUMORS COMPRISING SAME | 주식회사 대웅제약 | 2025-02-13 | — | — | WO | disclosed |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-10-17 | — | — | US | disclosed |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-10-17 | — | — | US | disclosed |
| US-20230318037-A1 | METHOD FOR PREPARING A LITHIUM ION SECONDARY BATTERY AND A LITHIUM ION SECONDARY BATTERY PREPARED THEREFROM | MURATA MANUFACTURING CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2023-05-11 | — | — | US | disclosed |
| US-11342514-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2022-05-24 | — | — | US | disclosed |
| WO-2021079743-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION AND HIGH-FREQUENCY PHASE SHIFTER | DIC株式会社 | 2021-04-29 | — | — | WO | disclosed |
| US-20200259106-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | SAMSUNG ELECTRONICS CO LTD (KR) | 2020-08-13 | — | — | US | disclosed |
| US-20100219407-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20100219407-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2010-09-02 | — | — | US | disclosed |
| US-20090306096-A1 | Novel Isoxazoles and Methods of Use Thereof | ABBOTT LABORATORIES (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2009149135-A1 | BIS (HETERO ) ARYL SUBSTITUTED ISOXAZOLES FOR USE AS NEURONAL NICOTINIC RECEPTOR MODULATORS | ABBOTT LABORATORIES (US) | 2009-12-10 | — | — | WO | disclosed |
| EP-1729771-B1 | PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2009-10-14 | — | — | EP | disclosed |
| WO-2009060995-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2009-05-14 | — | — | WO | disclosed |
| US-20080194647-A1 | Pyridyl Derivatives and Their Use as Mglu5 Antagonists | ELI LILLY AND COMPANY (US) | 2008-08-14 | — | — | US | disclosed |
| EP-1729771-A1 | PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS | Eli Lilly & Company (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005094822-A1 | PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140113862-A1 | METHOD FOR SITE-SPECIFIC POLYVALENT DISPLAY ON POLYMERS | NGLY1, DNPEP, GPKOW | GRM5 407/4885HDAC8 4854/4885ACHE 4396/4885 |
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | HSD17B1, HSD17B13, HSD17B3 | GRM5 2220/4885HDAC8 1242/4885ACHE 3606/4885 |
| US-20090306096-A1 | Novel Isoxazoles and Methods of Use Thereof | XDH, PRDX5, CYP4X1 | GRM5 1012/4885HDAC8 891/4885ACHE 1118/4885 |
| US-20200259106-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | L1CAM, AP2M1, MRPL9 | GRM5 840/4885HDAC8 4803/4885ACHE 2779/4885 |
| US-20100219407-A1 | ORGANIC METAL COMPLEX, AND ORGANIC LIGHT EMITTING DEVICE AND DISPLAY APPARATUS USING THE SAME | L1CAM, AP2M1, MRPL9 | GRM5 840/4885HDAC8 4803/4885ACHE 2779/4885 |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | L1CAM, AP2M1, MRPL9 | GRM5 840/4885HDAC8 4803/4885ACHE 2779/4885 |
| US-11342514-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | L1CAM, AP2M1, MRPL9 | GRM5 840/4885HDAC8 4803/4885ACHE 2779/4885 |
| US-20080194647-A1 | Pyridyl Derivatives and Their Use as Mglu5 Antagonists | HRH4, CNR2, CNR1 | GRM5 48/4885HDAC8 1957/4885ACHE 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.