Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | COMT | P21964 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656427 | 0.83 | ALDH1A1 (0.38) | FTOCOMTALDH1A1HPGD | |
| SCHEMBL12082558 | 0.77 | LMNA (0.47) | MAOAMAOBCDK2ALDH1A1KMT2A | |
| SCHEMBL14775910 | 0.75 | FTO (0.35) | FTOMAOAMAOBCDK2ALDH1A1 | |
| SCHEMBL12082320 | 0.75 | CDK2 (0.52) | CDK2ALDH1A1HPGDKMT2A | |
| SCHEMBL12717678 | 0.74 | FTO (0.40) | FTOMAOAMAOBCOMTALDH1A1 | |
| SCHEMBL14775733 | 0.73 | CDK2 (0.40) | CDK2COMTALDH1A1HPGDKMT2A | |
| SCHEMBL12082482 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDKMT2A | |
| SCHEMBL27825688 | 0.70 | CDK2 (0.51) | CDK2COMTALDH1A1HPGDKMT2A | |
| SCHEMBL1658633 | 0.68 | LMNA (0.48) | CDK2ALDH1A1HPGDKMT2A | |
| SCHEMBL121301 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |