Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14775871 | 0.78 | LMNA (0.41) | ALDH1A1HPGDFEN1 | |
| SCHEMBL14775936 | 0.77 | FBP1 (0.37) | ALDH1A1 | |
| SCHEMBL14775633 | 0.75 | FTO (0.44) | FTOALDH1A1HPGDPLA2G7CDK2 | |
| SCHEMBL14775713 | 0.75 | PKM (0.32) | ALDH1A1 | |
| SCHEMBL1656427 | 0.72 | ALDH1A1 (0.38) | FTOALDH1A1HPGD | |
| SCHEMBL9489749 | 0.71 | IMPDH2 (0.38) | — | |
| SCHEMBL12082482 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HPGD | |
| SCHEMBL5590503 | 0.67 | LDHA (0.36) | — | |
| SCHEMBL12717678 | 0.65 | FTO (0.40) | FTOALDH1A1HPGDPLA2G7MAOA | |
| SCHEMBL121301 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305633-B1 | Catechol derivative and its use | KISSEI PHARMACEUTICAL (JP) | 2013-03-20 | — | — | EP | claimed |