⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213587 | 0.74 | GGT1 (0.34) | — | |
| SCHEMBL11277663 | 0.71 | — | — | |
| SCHEMBL6558588 | 0.70 | GGT1 (0.39) | — | |
| SCHEMBL7257758 | 0.67 | CASP2 (0.33) | — | |
| SCHEMBL6881655 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL6881661 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL9798002 | 0.65 | — | — | |
| SCHEMBL3598285 | 0.65 | — | — | |
| SCHEMBL8200805 | 0.65 | CTSC (0.40) | — | |
| SCHEMBL19934807 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353190-B2 | Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) | 2016-05-31 | — | — | US | disclosed |
| US-20140113836-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH AZETIDINE-2-CARBOXYLIC ACID | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2014-04-24 | — | — | US | disclosed |
| US-8617624-B2 | Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-12-31 | — | — | US | disclosed |
| US-20110088457-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH AZETIDINE-2-CARBOXYLIC ACID | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-04-21 | — | — | US | disclosed |
| US-7915380-B2 | Compositions, systems and methods for the diagnosis, prevention and treatment of disorders associated with azetidine-2-carboxylic acid | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-20090140136-A1 | Method Of Analyzing Protein | NEC CORPORATION (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20070231313-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH AZETIDINE-2-CARBOXYLIC ACID | STANFORD UNIVERSITY (US) | 2007-10-04 | — | — | US | disclosed |