Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213587 | 0.79 | GGT1 (0.34) | GGT1 | |
| SCHEMBL875234 | 0.79 | TET2 (0.37) | LMNACYP2D6NFKB1MAPTFOLH1 | |
| SCHEMBL2199118 | 0.77 | AKR1B1 (0.44) | TSHRKMT2AHDAC11 | |
| SCHEMBL6312846 | 0.77 | GABRP (0.39) | LMNACYP2D6NFKB1MAPTFOLH1 | |
| SCHEMBL6312150 | 0.76 | GPR84 (0.46) | TSHRKMT2AHDAC11 | |
| SCHEMBL3940840 | 0.74 | CTSC (0.41) | LMNACYP2D6NFKB1MAPTFOLH1 | |
| SCHEMBL7357915 | 0.74 | KEAP1 (0.49) | LMNACYP2D6MAPTCYP1A2HDAC3 | |
| SCHEMBL4461170 | 0.73 | LMNA (0.39) | LMNACYP2D6NFKB1MAPTFOLH1 | |
| SCHEMBL7447970 | 0.73 | GGT1 (0.62) | GGT1FOLH1CYP1A2GRM8GRM6 | |
| SCHEMBL28078777 | 0.73 | GGT1 (0.62) | GGT1FOLH1CYP1A2GRM8GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790623-B2 | INCREASING DISCRIMINATING CAPABILITY OF HYBRIDIZATION ASSAYS VIA COMBINATION OF LABELLED PRIMERS WHICH REPLICATE ONE STRAND OF A NUCLEIC ACID HAVING COMPLEMENTARY CAPTURE PROBE | ROCHE DIAGNOSTICS GMBH (DE) | 2004-09-14 | — | — | US | disclosed |
| US-20030152937-A1 | DNA detection by means of a strand reassociation complex | ROCHE DIAGNOSTICS GMBH | 2003-08-14 | — | — | US | disclosed |
| US-6410235-B1 | DNA detection by means of a strand reassociation complex | ROCHE DIAGNOSTICS GMBH (DE) | 2002-06-25 | — | — | US | disclosed |