Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGDS | O60760 | 8/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | TPH1 | P17752 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727511 | 0.85 | TPH1 (0.50) | TPH1SIRT2MEN1LMNAKMT2A | |
| SCHEMBL8298247 | 0.85 | TPH1 (0.50) | TPH1SIRT2MEN1LMNAKMT2A | |
| SCHEMBL15314366 | 0.84 | TPH1 (0.47) | ALDH1A1TPH1MEN1LMNAMAPT | |
| SCHEMBL26751802 | 0.77 | EGFR (0.45) | ALDH1A1MEN1LMNAMAPTKMT2A | |
| SCHEMBL27477965 | 0.75 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL5916451 | 0.75 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL1108340 | 0.75 | ALDH1A1 (0.51) | ALDH1A1 | |
| SCHEMBL14780596 | 0.74 | CPB2 (0.52) | ALDH1A1 | |
| SCHEMBL29162421 | 0.73 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL7980841 | 0.73 | CYP1A2 (0.50) | ALDH1A1TPH1SIRT2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399614-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2013-03-19 | — | — | US | disclosed |