Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 5/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478590 | 0.83 | — | — | |
| SCHEMBL1478819 | 0.82 | HRH3 (0.34) | RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL1478409 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HTTHPGDHSD17B10RAB9A | |
| SCHEMBL1477947 | 0.77 | CHKA (0.37) | HTTRAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8460883 | 0.73 | CA1 (0.44) | ALDH1A1HPGDMAPT | |
| SCHEMBL1479659 | 0.71 | — | — | |
| SCHEMBL1479567 | 0.70 | FAAH (0.38) | ALDH1A1HTTHPGDRAB9AUSP2 | |
| SCHEMBL10917868 | 0.69 | HPGD (0.54) | ALDH1A1HPGDALOX15SMN1; SMN2MAPT | |
| SCHEMBL9194433 | 0.69 | HTT (0.44) | ALDH1A1HTTHPGDSMN1; SMN2MAPT | |
| SCHEMBL12212913 | 0.68 | PDCD1 (0.46) | ALDH1A1HPGDHSD17B10RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | disclosed |
| EP-2483317-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | Bridgestone Corporation (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| WO-2011041534-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-04-07 | — | — | WO | disclosed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |