Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.66 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.38 |
| ▸ | FNTB | P49356 | 2/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774705 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL24829528 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL18383664 | 0.88 | GSTK1 (0.65) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL26819626 | 0.85 | PTGS1 (0.62) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| Glutathione SCHEMBL27980028 | 0.84 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL27980029 | 0.84 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| SCHEMBL7594016 | 0.84 | PTGS1 (0.64) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL7594008 | 0.84 | PTGS1 (0.64) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL26483467 | 0.84 | PTGS1 (0.60) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL25794312 | 0.83 | PTGS1 (0.46) | PTGS1GSTK1NMT2NMT1SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1545512-B1 | Gold (III) complexes as anti-tumor and anti-HIV agents | UNIV HONG KONG (CN) | 2013-03-20 | — | — | EP | disclosed |