Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 8/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.48 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729945 | 0.91 | CES2 (0.53) | TRPM8LMNATSHRCES2CES1 | |
| SCHEMBL305837 | 0.91 | CES2 (0.53) | TRPM8LMNATSHRCES2CES1 | |
| SCHEMBL772236 | 0.86 | KMO (0.53) | HSD17B2ERN1LMNAHPGDTSHR | |
| SCHEMBL12469445 | 0.84 | ERN1 (0.59) | RELAERN1CES2CES1OPRM1 | |
| SCHEMBL30678242 | 0.82 | NPC1 (0.49) | TRPM8HPGDCES2CES1OPRM1 | |
| SCHEMBL3874243 | 0.82 | HSD17B2 (0.48) | HSD17B2ERN1LMNAHPGDTSHR | |
| SCHEMBL15281239 | 0.82 | KMT2A (0.50) | TRPM8HSD17B2LMNAHPGDTSHR | |
| SCHEMBL14786153 | 0.81 | TRPM8 (0.53) | TRPM8RELA | |
| SCHEMBL30790370 | 0.78 | ERN1 (0.58) | RELAERN1LMNATSHR | |
| SCHEMBL7829981 | 0.78 | ERN1 (0.58) | RELAERN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755944-A2 | ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | Fovea Pharmaceuticals (FR) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013037705-A9 | ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | FOVEA PHARMACEUTICALS (FR) | 2013-09-06 | — | — | WO | disclosed |
| WO-2013037705-A2 | ANILINE DERIVATIVES,THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | FOVEA PHARMACEUTICALS (FR) | 2013-03-21 | — | — | WO | disclosed |