Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13152227 | 0.95 | DPP4 (0.41) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL13868392 | 0.93 | DPP4 (0.40) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL24159881 | 0.92 | ALDH1A1 (0.39) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL2607300 | 0.92 | ALDH1A1 (0.39) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL13174481 | 0.92 | ALDH1A1 (0.39) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL13569454 | 0.92 | POLB (0.40) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL2951416 | 0.91 | NPC1 (0.43) | DPP4NPC1RAB9APOLBALDH1A1 | |
| SCHEMBL16489732 | 0.90 | FGF23 (0.41) | DPP4NFE2L2 | |
| SCHEMBL8387028 | 0.90 | FGF23 (0.41) | DPP4NFE2L2 | |
| SCHEMBL8916491 | 0.90 | FGF23 (0.41) | DPP4NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071780-A1 | TRIPHENYLAMINE DERIVATIVES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071780-A1 | TRIPHENYLAMINE DERIVATIVES | SLC29A1, SLC7A1, SLC7A5 | DPP4 3760/4885NPC1 335/4885RAB9A 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.