SCHEMBL13152227

SCHEMBL13152227

Cc1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccc(C)cc5)c5ccc6c(c5)CCCC6)cc4)cc3)cc2)c2ccc3c(c2)CCCC3)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 1/20 0.41
▸ NPC1 O15118 3/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ POLB P06746 1/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ MAPT P10636 3/20 0.38
▸ LMNA P02545 2/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ THRB P10828 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ ADCY8 P40145 1/20 0.38
▸ ADCY1 Q08828 1/20 0.38
▸ RXRA P19793 1/20 0.38
▸ RXRB P28702 1/20 0.38
▸ RXRG P48443 1/20 0.38
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2951416 0.97 NPC1 (0.43) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL14786637 0.95 DPP4 (0.44) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL11950306 0.93 ALDH1A1 (0.36) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL14036936 0.92 NPC1 (0.42) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL13868392 0.88 DPP4 (0.40) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL24159881 0.87 ALDH1A1 (0.39) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL2607300 0.87 ALDH1A1 (0.39) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL13174481 0.87 ALDH1A1 (0.39) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL13569454 0.87 POLB (0.40) DPP4NPC1RAB9APOLBSMN1; SMN2
SCHEMBL12606451 0.87 KCNA1 (0.37) NPC1RAB9APOLBSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9880477-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-01-30 — — US disclosed
US-9880477-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-01-30 — — US disclosed
US-20170003607-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-01-05 — — US disclosed
US-20170003607-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-01-05 — — US disclosed
US-20160091806-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2016-03-31 — — US disclosed
US-20160091806-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2016-03-31 — — US disclosed
US-9195154-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2015-11-24 — — US disclosed
US-9195154-B2 Electrophotographic photoreceptor and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2015-11-24 — — US disclosed
US-9029053-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-12 — — US disclosed
US-9029053-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-12 — — US disclosed
US-20130209928-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-15 — — US disclosed
US-20130209929-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-15 — — US disclosed
US-20130209928-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-15 — — US disclosed
US-20130209929-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-15 — — US disclosed
US-7799492-B2 P-terphenyl compound and photosensitive body for electrophotography using such compound HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-21 — — US disclosed
US-7799492-B2 P-terphenyl compound and photosensitive body for electrophotography using such compound HODOGAYA CHEMICAL CO., LTD. (JP) 2010-09-21 — — US disclosed
US-7759030-B2 P-terphenyl compound and photosensitive body for electrophotography using such compound HODOGAYA CHEMICAL CO., LTD. (JP) 2010-07-20 — — US disclosed
US-20100015542-A1 N,N,N',N'- phenyl substituted diamino p-terphenyl; improved solubility in an organic solvent, charge transporting agent, electrophotographic photoconductor; N,N'-bisindane-5-yl-N,N'-di-p-tolyl-4,4''-diamino-p-terphenyl HODOGAYA CHEMICAL CO., LTD. (JP) 2010-01-21 — — US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 — — US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound SLCO2A1, SLCO2B1, SLC26A4 DPP4 2026/4885NPC1 1320/4885RAB9A 2267/4885
US-20100015542-A1 N,N,N',N'- phenyl substituted diamino p-terphenyl; improved solubility in an organic solvent, charge transporting agent, electrophotographic photoconductor; N,N'-bisindane-5-yl-N,N'-di-p-tolyl-4,4''-diamino-p-terphenyl SLC43A3, SLC29A2, SLCO2A1 DPP4 1075/4885NPC1 460/4885RAB9A 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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