SCHEMBL13174481

SCHEMBL13174481

Cc1ccc(N(c2ccc(N(c3ccc(C)cc3)c3ccc4c(c3)CC4)cc2)c2ccc3c(c2)CC3)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.39
▸ TSHR P16473 1/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ NFKB2 Q00653 1/20 0.39
▸ RELA Q04206 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ LMNA P02545 2/20 0.36
▸ DPP4 P27487 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ ACHE P22303 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ RXRA P19793 1/20 0.33
▸ RXRB P28702 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24159881 1.00 ALDH1A1 (0.39) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL2607300 1.00 ALDH1A1 (0.39) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL11950306 0.94 ALDH1A1 (0.36) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL17430706 0.93 ALDH1A1 (0.39) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL14786637 0.92 DPP4 (0.44) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL14226932 0.91 ALDH1A1 (0.45) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL22686625 0.89 TSHR (0.50) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL25965002 0.89 TSHR (0.50) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL17852993 0.89 NPC1 (0.43) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL12606451 0.88 KCNA1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-03 — — US disclosed
US-9929347-B2 Polymer compound and light emitting element using same SUMITOMO CHEMICAL COMPANY, LIMTIED (JP) 2018-03-27 — — US disclosed
US-20180022990-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-25 — — US disclosed
US-20170283546-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-05 — — US disclosed
US-9780308-B2 Composition and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-03 — — US disclosed
US-20170253795-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-09-07 — — US disclosed
US-9741934-B2 Polymer compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-22 — — US disclosed
US-20170222163-A1 LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 — — US disclosed
US-20170194584-A1 LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-06 — — US disclosed
US-20170117491-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED IN THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-27 — — US disclosed
US-20170040542-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-09 — — US disclosed
US-9331284-B2 Polymer compound and light-emitting device using same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-05-03 — — US disclosed
US-20150115204-A1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2015-04-30 — — US disclosed
US-20140367617-A1 POLYMER COMPOUND, COMPOSITION, AND LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-18 — — US disclosed
US-20140183414-A1 POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-07-03 — — US disclosed
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2012-12-27 — — US disclosed
US-20120306358-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-06 — — US disclosed
EP-2518110-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION Sumitomo Chemical Company, Limited (JP) 2012-10-31 — — EP disclosed
US-20120256537-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-11 — — US disclosed
US-20120256537-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117491-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED IN THE SAME CYBA, CRY1, AP2A1 ALDH1A1 8/4885TSHR 4738/4885NPC1 4055/4885
US-20120326140-A1 POLYMER COMPOUND AND LIGHT-EMITTING DEVICE USING SAME CCNA1, CCNB1, CCNL2 ALDH1A1 592/4885TSHR 2469/4885NPC1 2855/4885
US-20170040542-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME CRY1, CHRM1, CRY2 ALDH1A1 407/4885TSHR 3228/4885NPC1 2109/4885
US-20150115204-A1 POLYMER COMPOUND AND LIGHT EMITTING ELEMENT USING SAME NAP1L4, AHR, NR0B1 ALDH1A1 1239/4885TSHR 3348/4885NPC1 3337/4885
US-20170194584-A1 LIGHT EMITTING DEVICE CRY1, CCNE2, L1CAM ALDH1A1 63/4885TSHR 2754/4885NPC1 4144/4885
US-20180123056-A1 LIGHT EMITTING DEVICE AND COMPOSITION USED FOR THIS LIGHT EMITTING DEVICE CHRM1, CRY1, L1CAM ALDH1A1 59/4885TSHR 3346/4885NPC1 3836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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