SCHEMBL2951416

SCHEMBL2951416

Cc1ccc(N(c2ccc(-c3ccc(-c4ccc(N(c5ccc(C)cc5)c5ccc6c(c5)CCC6)cc4)cc3)cc2)c2ccc3c(c2)CCC3)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 5/20 0.43
▸ RAB9A P51151 5/20 0.43
▸ POLB P06746 1/20 0.43
▸ ALDH1A1 P00352 4/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ NFKB1 P19838 1/20 0.41
▸ NFKB2 Q00653 1/20 0.41
▸ RELA Q04206 1/20 0.41
▸ THRB P10828 1/20 0.41
▸ RAPGEF4 Q8WZA2 1/20 0.38
▸ DPP4 P27487 1/20 0.38
▸ RXRA P19793 1/20 0.38
▸ RXRB P28702 1/20 0.38
▸ RXRG P48443 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ADCY8 P40145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13152227 0.97 DPP4 (0.41) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL11950306 0.93 ALDH1A1 (0.36) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL14786637 0.91 DPP4 (0.44) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL14036936 0.89 NPC1 (0.42) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL24159881 0.87 ALDH1A1 (0.39) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL2607300 0.87 ALDH1A1 (0.39) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL13174481 0.87 ALDH1A1 (0.39) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL12606451 0.87 KCNA1 (0.37) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL12619835 0.86 ADCY8 (0.36) NPC1RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL12619670 0.86 ADCY8 (0.36) NPC1RAB9APOLBALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1752441-B1 P-TERPHENYL COMPOUND AND PHOTOSENSITIVE BODY FOR ELECTROPHOTOGRAPHY USING SUCH COMPOUND HODOGAYA CHEMICAL CO LTD (JP) 2016-12-21 — — EP disclosed
EP-1752441-B1 P-TERPHENYL COMPOUND AND PHOTOSENSITIVE BODY FOR ELECTROPHOTOGRAPHY USING SUCH COMPOUND HODOGAYA CHEMICAL CO LTD (JP) 2016-12-21 — — EP disclosed
EP-1995234-B1 p-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME HODOGAYA CHEMICAL CO LTD (JP) 2016-01-06 — — EP disclosed
EP-2518046-B1 P-Terphenyl compound and electrophotographic photoconductor using the same HODOGAYA CHEMICAL CO LTD (JP) 2014-12-10 — — EP disclosed
EP-2518046-B1 P-Terphenyl compound and electrophotographic photoconductor using the same HODOGAYA CHEMICAL CO LTD (JP) 2014-12-10 — — EP disclosed
EP-1818725-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY HODOGAYA CHEMICAL CO LTD (JP) 2014-09-10 — — EP disclosed
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 — — US disclosed
US-8808951-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2014-08-19 — — US disclosed
EP-2759531-A1 P-Terphenyl compound and electrophotographic photoconductor using the same Hodogaya Chemical Co., Ltd. (JP) 2014-07-30 — — EP disclosed
US-8673792-B2 p-Terphenyl compound mixture and electrophotographic photoreceptors made by using the same HODOGAYA CHEMICAL CO., LTD. (JP) 2014-03-18 — — US disclosed
US-20090053633-A1 P-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2009-02-26 — — US disclosed
EP-1995234-A1 p-TERPHENYL COMPOUND MIXTURE AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS MADE BY USING THE SAME Hodogaya Chemical Co., Ltd. (JP) 2008-11-26 — — EP disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 — — US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 — — US disclosed
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-03-27 — — US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 — — US disclosed
US-20080044750-A1 Electrophotographic Photosensitive Body HODOGAYA CHEMICAL CO., LTD. (JP) 2008-02-21 — — US disclosed
EP-1818725-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Hodogaya Chemical Co., Ltd. (JP) 2007-08-15 — — EP disclosed
EP-1816522-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY Hodogaya Chemical Co., Ltd. (JP) 2007-08-08 — — EP disclosed
EP-1752441-A1 P-TERPHENYL COMPOUND AND PHOTOSENSITIVE BODY FOR ELECTROPHOTOGRAPHY USING SUCH COMPOUND Hodogaya Chemical Co., Ltd. (JP) 2007-02-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076050-A1 P-Terphenyl Compound And Photosensitve Body For Electrophotography Using Such Compound SLCO2A1, SLCO2B1, SLC26A4 NPC1 1320/4885RAB9A 2267/4885POLB 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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