SCHEMBL1478808

SCHEMBL1478808

COc1ccc(C=CC(=O)OC#N)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F3 P13726 3/20 0.62
▸ THRB P10828 1/20 0.60
▸ ATM Q13315 1/20 0.60
▸ GSK3B P49841 2/20 0.58
▸ MAPT P10636 3/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ HDAC3 O15379 2/20 0.57
▸ HDAC1 Q13547 2/20 0.57
▸ HDAC2 Q92769 2/20 0.57
▸ HDAC8 Q9BY41 2/20 0.57
▸ HDAC6 Q9UBN7 2/20 0.57
▸ BACE1 P56817 1/20 0.54
▸ LMNA P02545 1/20 0.54
▸ TDP1 Q9NUW8 1/20 0.54
▸ HDAC4 P56524 1/20 0.53
▸ HDAC7 Q8WUI4 1/20 0.53
▸ HDAC10 Q969S8 1/20 0.53
▸ HDAC11 Q96DB2 1/20 0.53
▸ HDAC9 Q9UKV0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22026690 1.00 F3 (0.62) F3THRBATMGSK3BMAPT
SCHEMBL1299521 0.81 CA12 (0.61) F3GSK3BKMT2AHDAC3HDAC1
SCHEMBL2547176 0.81 CA12 (0.61) F3GSK3BKMT2AHDAC3HDAC1
SCHEMBL1397478 0.81 GSK3B (0.73) F3THRBATMGSK3BMAPT
SCHEMBL18121572 0.81 KMT2A (0.76) F3THRBATMGSK3BMAPT
SCHEMBL1237222 0.81 GSK3B (0.73) F3THRBATMGSK3BMAPT
SCHEMBL30105639 0.81 GSK3B (0.73) F3THRBATMGSK3BMAPT
SCHEMBL6276084 0.80 LMNA (0.60) F3THRBATMGSK3BMAPT
SCHEMBL8346575 0.80 SNCA (0.59) F3THRBATMGSK3BMAPT
SCHEMBL10921920 0.80 F3 (0.66) F3THRBATMGSK3BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0551510-B1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE OREAL (FR) 1995-09-27 — — EP claimed
EP-0551510-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE. OREAL (FR) 1993-07-21 — — EP claimed
WO-1993002659-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE L'OREAL (FR) 1993-02-18 — — WO claimed
US-12474513-B2 Blue light blocking film layer and blue light blocking system EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2025-11-18 — — US disclosed
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2023-10-05 — — US disclosed
CN-109384878-B Blue light prevention system containing pyrazoline or/and phenylpropenoic compound 江苏裕事达新材料科技有限责任公司 2023-01-24 — — CN disclosed
CN-113698417-B Spiro compound and preparation method and application thereof 上海凯毕淬化学科技有限公司 2022-07-01 — — CN disclosed
CN-113698417-A Spiro compound and preparation method and application thereof 上海凯毕淬化学科技有限公司 2021-11-26 — — CN disclosed
US-20200181363-A1 BLUE LIGHT BLOCKING SYSTEM CONTAINING PYRAZOLINE OR/AND PHENYLACRYLIC COMPOUNDS EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2020-06-11 — — US disclosed
EP-1860158-B1 Particles comprising a substrate and an anion-binding layer MERCK PATENT GMBH (DE) 2013-12-04 — — EP disclosed
US-7914893-B2 Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof MERCK PATENT GMBH (DE) 2011-03-29 — — US disclosed
US-20070275244-A1 Particles MERCK PATENT GMBH 2007-11-29 — — US disclosed
EP-1860158-A2 Particles comprising a substrate and an anion-binding layer MERCK PATENT GmbH (DE) 2007-11-28 — — EP disclosed
EP-0551510-B1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE OREAL (FR) 1995-09-27 — — EP disclosed
EP-0551510-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE. OREAL (FR) 1993-07-21 — — EP disclosed
WO-1993002659-A1 PHOTOSTABLE FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND A 4-METHOXY BENZYLIDENE CYANOACETATE L'OREAL (FR) 1993-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181363-A1 BLUE LIGHT BLOCKING SYSTEM CONTAINING PYRAZOLINE OR/AND PHENYLACRYLIC COMPOUNDS CUTA, PASK, SERPINE1 F3 319/4885THRB 1159/4885ATM 416/4885
US-20230314675-A1 BLUE LIGHT BLOCKING FILM LAYER AND BLUE LIGHT BLOCKING SYSTEM CRY1, CRY2, BLVRB F3 2583/4885THRB 158/4885ATM 2998/4885
US-12474513-B2 Blue light blocking film layer and blue light blocking system CRY1, CRY2, BLVRB F3 2583/4885THRB 158/4885ATM 2998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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