Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14786950 | 0.87 | KEAP1 (0.39) | L3MBTL1MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL14788566 | 0.79 | MEN1 (0.66) | LMNAL3MBTL1MEN1KMT2ACYP1A2 | |
| SCHEMBL22939500 | 0.78 | LMNA (0.48) | GAALMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL12696372 | 0.78 | ATM (0.45) | GAALMNAMEN1KMT2AHTT | |
| SCHEMBL2590633 | 0.69 | CA12 (0.48) | GAALMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL1731363 | 0.66 | GAA (0.53) | GAALMNAL3MBTL1KEAP1NFE2L2 | |
| SCHEMBL11875228 | 0.66 | ALDH1A1 (0.43) | GAALMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL3456256 | 0.65 | KMT2A (0.56) | LMNAMEN1KMT2AHTTCA12 | |
| SCHEMBL11872172 | 0.65 | KMT2A (0.47) | GAALMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL20565896 | 0.65 | NPC1 (0.58) | GAALMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071328-A1 | Propynoic Acid Carbamoyl Methyl-Amides and Pharmaceutical Compositions and Methods Based Thereon | RELA, NFE2, NCOA1 | GAA 2437/4885LMNA 1318/4885L3MBTL1 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.