Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 10/20 | 0.72 |
| ▸ | MMP2 | P08253 | 9/20 | 0.72 |
| ▸ | MMP3 | P08254 | 4/20 | 0.72 |
| ▸ | MMP13 | P45452 | 4/20 | 0.57 |
| ▸ | MMP8 | P22894 | 4/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646070 | 0.86 | MMP9 (0.74) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL300824 | 0.86 | MMP2 (0.70) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL11143027 | 0.84 | MMP9 (0.68) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL14782939 | 0.84 | MMP2 (0.72) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL300798 | 0.82 | MMP2 (0.69) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL12457432 | 0.80 | MMP9 (0.67) | MMP9MMP2MMP3MMP13MMP8 | |
| Phenobarbital SCHEMBL11529160 | 0.75 | MMP9 (0.73) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL10903887 | 0.74 | MMP9 (0.55) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL264852 | 0.74 | MMP2 (0.54) | MMP9MMP2MMP3MMP13MMP8 | |
| SCHEMBL6810540 | 0.74 | MMP2 (1.00) | MMP9MMP2MMP3MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |