Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.54 |
| ▸ | MMP9 | P14780 | 14/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 10/20 | 0.47 |
| ▸ | MMP8 | P22894 | 9/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301236 | 0.89 | MMP2 (0.43) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL264568 | 0.86 | MMP2 (0.43) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL13889220 | 0.81 | MMP2 (0.40) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL264182 | 0.80 | ALDH1A1 (0.48) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL300824 | 0.78 | MMP2 (0.70) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL11143027 | 0.77 | MMP9 (0.68) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL379163 | 0.75 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL905700 | 0.75 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL1870550 | 0.75 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL905404 | 0.75 | SMN1; SMN2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| EP-2205571-B1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2205571-B1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2011-08-31 | — | — | EP | disclosed |
| EP-2205571-A1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | Roche Diagnostics GmbH (DE) | 2010-07-14 | — | — | EP | disclosed |
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-04-23 | — | — | US | disclosed |
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-04-23 | — | — | US | disclosed |
| WO-2009049884-A1 | PHENOBARBITAL DERIVATIVES USEFUL IN IMMUNOASSAY | ROCHE DIAGNOSTICS GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | PGM2, CYP4F2, CYP3A7 | MMP2 1480/4885MMP9 2113/4885MMP3 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.