Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.69 |
| ▸ | MMP9 | P14780 | 10/20 | 0.69 |
| ▸ | MMP3 | P08254 | 4/20 | 0.69 |
| ▸ | MMP13 | P45452 | 4/20 | 0.55 |
| ▸ | MMP8 | P22894 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14782939 | 0.85 | MMP2 (0.72) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL14788892 | 0.82 | MMP9 (0.72) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL11143027 | 0.82 | MMP9 (0.68) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL300824 | 0.81 | MMP2 (0.70) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL12457432 | 0.78 | MMP9 (0.67) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL7646070 | 0.77 | MMP9 (0.74) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL14788914 | 0.75 | MMP2 (0.62) | MMP2MMP9MMP3MMP13MMP8 | |
| Phenobarbital SCHEMBL17372721 | 0.75 | MMP9 (0.57) | MMP2MMP9MMP3MMP13MMP8 | |
| SCHEMBL300807 | 0.74 | MMP2 (0.49) | MMP2MMP9MMP3MMP13MMP8 | |
| Phenobarbital SCHEMBL2323476 | 0.73 | MMP2 (0.51) | MMP2MMP9MMP3MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133743-B2 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2009-04-23 | — | — | US | disclosed |
| US-4404366-A | ENZYME CLEAVABLE GLYCOSIDIC LINKAGE | MILES LABORATORIES, INC. (US) | 1983-09-13 | — | — | US | disclosed |
| US-4363874-A | RADIOIMMUNOASSAY DIAGNOSIS | MILES LABORATORIES, INC. (US) | 1982-12-14 | — | — | US | disclosed |
| US-4331590-A | β-Galactosyl-umbelliferone-labeled protein and polypeptide conjugates | MILES LABORATORIES, INC. (US) | 1982-05-25 | — | — | US | disclosed |
| US-4279992-A | Specific binding assay employing an enzyme-cleavable substrate as label | MILES LABORATORIES, INC. (US) | 1981-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104713-A1 | Phenobarbital derivatives useful in immunoassay | PGM2, CYP4F2, CYP3A7 | MMP2 1480/4885MMP9 2113/4885MMP3 3968/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.