Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7266498 | 0.93 | ALDH1A1 (0.46) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL7139929 | 0.89 | ALDH1A1 (0.49) | ALDH1A1LMNAKCNJ1KCNH2KMT2A | |
| SCHEMBL20593805 | 0.85 | CRHBP (0.45) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL2370645 | 0.84 | MMP8 (0.52) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL811589 | 0.84 | LMNA (0.47) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL31275152 | 0.83 | LMNA (0.46) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL8940532 | 0.82 | MAOB (0.52) | ALDH1A1POLBMAPTSMN1; SMN2GAA | |
| SCHEMBL3146193 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBMAPTGAARAB9A | |
| SCHEMBL812176 | 0.81 | LMNA (0.44) | ALDH1A1POLBLMNAKCNJ1KCNH2 | |
| SCHEMBL812175 | 0.81 | LMNA (0.44) | ALDH1A1POLBLMNAKCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |