Butethal

Butethal

SCHEMBL44262

CCCCC1(CC)C(=O)NC(=O)NC1=O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
MMP9 P14780 7/20 0.53
MMP2 P08253 6/20 0.53
MMP13 P45452 5/20 0.53
MMP8 P22894 4/20 0.53
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.43
ELANE P08246 1/20 0.43
MMP3 P08254 1/20 0.42
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GABRB3 P28472 1/20 0.41
OPRD1 P41143 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
MEN1 O00255 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CRHBP P24387 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butethal SCHEMBL2718536 0.98 LMNA (0.64) LMNAMMP9MMP2MMP13MMP8
SCHEMBL918796 0.94 LMNA (0.64) LMNAMMP9MMP2MMP13MMP8
SCHEMBL712742 0.92 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4379822 0.92 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4382583 0.92 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4390355 0.92 MMP9 (0.63) LMNAMMP9MMP2MMP13MMP8
SCHEMBL1683293 0.91 LMNA (0.58) LMNAMMP9MMP2MMP13MMP8
SCHEMBL1641551 0.90 MMP9 (0.61) LMNAMMP9MMP2MMP13MMP8
Amobarbital SCHEMBL13723415 0.88 LMNA (0.52) LMNAMMP9MMP2MMP13MMP8
SCHEMBL4889487 0.86 LMNA (0.73) LMNAMMP9MMP2MMP13MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2750 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260041939-A1 METHODS FOR THE TREATMENT OF HYPERTENSION VIA TRANSCRANIAL-FOCUSED-ULTRASOUND SUNNYBROOK RES INST (CA) 2026-02-12 US claimed
EP-3507371-B1 COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM UNIV RUTGERS (US) 2026-01-28 EP claimed
US-20250249002-A1 PHARMACEUTICAL COMPOSITION FOR TOPICAL WOUND TREATMENT CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECN (AR) 2025-08-07 US claimed
US-12133922-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2024-11-05 US claimed
EP-4232004-A1 FRACTAL FORMULATIONS Nanogyre Sprl (BE) 2023-08-30 EP claimed
US-20230174613-A1 METHODS AND COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2023-06-08 US claimed
US-20230030204-A1 Treatment of Type 1 Diabetes Galvani Bioelectronics Limited (GB) 2023-02-02 US claimed
US-11542315-B2 Methods and compositions for treating diseases and disorders of the nervous system RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-01-03 US claimed
US-20220362160-A1 ABUSE RESISTANT CAPSULE R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-11-17 US claimed
US-11464747-B2 Abuse resistant capsule R.P. SCHERER TECHNOLOGIES, LLC (US) 2022-10-11 US claimed
EP-1165048-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS Lipocine, Inc. (US) 2002-01-02 EP claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
EP-1067942-A1 HIGH-ENERGY CYCLODEXTRIN COMPLEXES Cyclops, EHF. (IS) 2001-01-17 EP claimed
WO-2000059475-A1 COMPOSITIONS AND METHODS FOR IMPROVED DELIVERY OF IONIZABLE HYDROPHOBIC THERAPEUTIC AGENTS LIPOCINE, INC. (US) 2000-10-12 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
WO-1999042111-A1 HIGH-ENERGY CYCLODEXTRIN COMPLEXES CYCLOPS, EHF. (IS) 1999-08-26 WO claimed
US-4181719-A Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates STERLING DRUG INC. (US) 1980-01-01 US claimed
US-4107153-A Heat-resistant thermosetting polyimide resin TOSHIBA CHEMICAL PRODUCTS CO., LTD. (JP) 1978-08-15 US claimed
US-4097545-A Heat-resistant thermosetting polyimide resin with bis-phenol-epichlorohydrin reaction product TOSHIBA CHEMICAL PRODUCTS CO. LTD. (JA) 1978-06-27 US claimed