Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MMP9 | P14780 | 7/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | MMP13 | P45452 | 5/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butethal SCHEMBL44262 | 0.98 | LMNA (0.67) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL1641551 | 0.92 | MMP9 (0.61) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL918796 | 0.92 | LMNA (0.64) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL4382583 | 0.90 | MMP9 (0.63) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL712742 | 0.90 | MMP9 (0.63) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL4379822 | 0.90 | MMP9 (0.63) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL4390355 | 0.90 | MMP9 (0.63) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL1683293 | 0.89 | LMNA (0.58) | LMNAMMP9MMP2MMP13MMP8 | |
| Amobarbital SCHEMBL13723415 | 0.86 | LMNA (0.52) | LMNAMMP9MMP2MMP13MMP8 | |
| SCHEMBL4889487 | 0.85 | LMNA (0.73) | LMNAMMP9MMP2MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10076580-B2 | Gas-filled microvesicles composition for contrast imaging | BRACCO SUISSE S.A. (CH) | 2018-09-18 | — | — | US | disclosed |
| EP-1784228-B1 | GAS-FILLED MICROVESICLES COMPOSITION FOR CONTRAST IMAGING | BRACCO SUISSE SA (CH) | 2016-10-05 | — | — | EP | disclosed |
| US-20160184464-A1 | Gas-Filled Microvesicles Composition For Contrast Imaging | BRACCO SUISSE S.A. (CH) | 2016-06-30 | — | — | US | disclosed |
| US-9248204-B2 | Gas-filled microvesicles composition for contrast imaging | BRACCO SUISSE S.A. (CH) | 2016-02-02 | — | — | US | disclosed |
| CN-1960707-B | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH SA | 2012-11-14 | — | — | CN | disclosed |
| WO-2012059936-A1 | PHARMACEUTICAL COMPOSITIONS FOR COLLOIDAL DRUG DELIVERY | DEVARAJAN PADMA VENKITACHALAM (IN) | 2012-05-10 | — | — | WO | disclosed |
| US-7749485-B2 | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH S.A. (CH) | 2010-07-06 | — | — | US | disclosed |
| EP-1750671-B1 | LIPOSOMAL ASSEMBLY FOR THERAPEUTIC AND/OR DIAGNOSTIC USE | BRACCO RESEARCH SA (CH) | 2008-10-15 | — | — | EP | disclosed |
| CN-101237892-A | Method for conjugating molecules containing an aminothiol to a carrier | AMGEN INC (US) | 2008-08-06 | — | — | CN | disclosed |
| US-20080008657-A1 | Gas- Filled Microvesicles Composition for Contrast Imaging | BRACCO RESEARCH S.A. (CH) | 2008-01-10 | — | — | US | disclosed |
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20070196284-A1 | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH S.A. (CH) | 2007-08-23 | — | — | US | disclosed |
| EP-1784228-A1 | GAS-FILLED MICROVESICLES COMPOSITION FOR CONTRAST IMAGING | BRACCO RESEARCH S.A. (CH) | 2007-05-16 | — | — | EP | disclosed |
| CN-1960707-A | Liposomal assembly for therapeutic and/or diagnostic use | BRACCO RESEARCH SA (CH) | 2007-05-09 | — | — | CN | disclosed |
| EP-1750671-A1 | LIPOSOMAL ASSEMBLY FOR THERAPEUTIC AND/OR DIAGNOSTIC USE | BRACCO RESEARCH S.A. (CH) | 2007-02-14 | — | — | EP | disclosed |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | AMGEN INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006018433-A1 | GAS-FILLED MICROVESICLES COMPOSITION FOR CONTRAST IMAGING | BRACCO RESEARCH SA (CH) | 2006-02-23 | — | — | WO | disclosed |
| WO-2005117832-A1 | LIPOSOMAL ASSEMBLY FOR THERAPEUTIC AND/OR DIAGNOSTIC USE | BRACCO RESEARCH SA (CH) | 2005-12-15 | — | — | WO | disclosed |
| US-3950508-A | Process for obtaining pharmaceutical sustained releases | LABORATOIRES SERVIER (FR) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | SLC7A1, QPCT, SLC7A5 | LMNA 3830/4885MMP9 2784/4885MMP2 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.