SCHEMBL147899

SCHEMBL147899

Cc1cccc(C(=O)c2ccc(C(=O)OC(C)(C)C)c3ooc23)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
ADRB2 P07550 2/20 0.40
ADRB1 P08588 2/20 0.40
ADRB3 P13945 2/20 0.40
PARP1 P09874 1/20 0.40
SLC7A5 Q01650 1/20 0.39
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALOX15 P16050 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HTT P42858 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28539639 0.83 POLB (0.63) POLBPARP1HPGDHDAC8HDAC6
SCHEMBL1710257 0.81 HSD17B10 (0.41) ALOX15ALDH1A1
SCHEMBL2107215 0.78 PARP1 (0.53) POLBADRB2ADRB1ADRB3PARP1
SCHEMBL28417334 0.77 PARP1 (0.52) POLBADRB2ADRB1ADRB3PARP1
SCHEMBL5397433 0.73 EGFR (0.36)
SCHEMBL10934700 0.72 EGFR (0.41) TDP1KMT2A
SCHEMBL8897134 0.71 STAT3 (0.36) KMT2A
SCHEMBL28669909 0.70 POLB (0.60) POLBPARP1HPGDTDP1HDAC8
SCHEMBL6351061 0.70 CSNK2A1 (0.41) NPC1RAB9AKMT2ANPSR1
SCHEMBL5388885 0.70 ALDH1A1 (0.38) POLBHPGDTDP1ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3835329-B1 POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-05-01 EP disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
US-20230323084-A1 POLYMERIZATION INITIATOR, CURABLE COMPOSITION, DENTAL MATERIAL, AND PREPARATION KIT FOR CURABLE COMPOSITION MITSUI CHEMICALS, INC. (JP) 2023-10-12 US disclosed
US-11608438-B2 Low-dielectric heat dissipation film composition and low-dielectric heat dissipation film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-03-21 US disclosed
US-11597829-B2 Resin composition for fiber-reinforced composite materials and fiber-reinforced composite material using same NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-03-07 US disclosed
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME KURARAY NORITAKE DENTAL INC. (JP) 2023-02-16 US disclosed
CN-114854064-A Prepreg, method for producing same, and fiber-reinforced plastic molded body 三菱化学株式会社 2022-08-05 CN disclosed
CN-110088163-B Curable resin composition, and film, molded article, prepreg, and fiber-reinforced plastic using same 三菱化学株式会社 2022-06-14 CN disclosed
US-11352449-B2 Graft copolymer, and thermoplastic resin composition using same TECHNO-UMG CO., LTD. (JP) 2022-06-07 US disclosed
EP-2873410-B1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2022-05-04 EP disclosed
US-6733695-B2 SILVER POWDER AND THERMOSETTING RESIN SUMITOMO BAKELITE COMPANY LTD. (JP) 2004-05-11 US disclosed
US-20040081912-A1 Photosensitive polysilazane composition and method of forming patterned polysilazane film AZ ELECTRONIC MATERIALS USA CORP. 2004-04-29 US disclosed
US-20030122257-A1 Electrically conductive paste and semiconductor device prepared by using the paste RENESAS ELECTRONICS CORPORATION (JP) 2003-07-03 US disclosed
US-6465144-B2 ELECTROSTATIC LATENT IMAGE; CONTROL CHARGING CANON KABUSHIKI KAISHA (JP) 2002-10-15 US disclosed
US-20020009661-A1 Magnetic toner, process for production thereof, and image forming method, apparatus and process cartridge using the toner CANON KABUSHIKI KAISHA (JP) 2002-01-24 US disclosed
EP-1164435-A1 PHOTOSENSITIVE POLYSILAZANE COMPOSITION AND METHOD OF FORMING PATTERNED POLYSILAZANE FILM TonenGeneral Sekiyu K.K. (JP) 2001-12-19 EP disclosed
US-6306947-B1 Printing ink and paint composed of an aqueous emulsion of self-emulsifiable urethane copolymer NIPPON POLYURETHANE INDUSTRY CO., LTD. (JP) 2001-10-23 US disclosed
EP-1132781-A2 Magnetic toner, process for production thereof, and image forming method, apparatus and process cartridge using the toner CANON KABUSHIKI KAISHA (JP) 2001-09-12 EP disclosed
EP-1057843-A1 Aqueous emulsion, process for producing the same and aqueous paint and aqueous printing ink comprising the same NIPPON POLYURETHANE INDUSTRY CO. LTD. (JP) 2000-12-06 EP disclosed
EP-1006130-A1 Fumaric acid diester resin composition, cross-linked fumaric acid diester resin and process NOF CORPORATION (JP) 2000-06-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230049373-A1 PASTE-LIKE COMPOSITION FOR DENTAL USE, AND METHOD FOR PRODUCING THE SAME PFN1, XRN2, FLNA POLB 596/4885ADRB2 4789/4885ADRB1 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.