Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439796 | 0.92 | ALDH1A1 (0.32) | ALDH1A1MEN1KMT2ANR1I2RAB9A | |
| SCHEMBL14800157 | 0.80 | TSHR (0.39) | ALDH1A1TSHRAOC3RAB9ASMN1; SMN2 | |
| SCHEMBL14799603 | 0.76 | TSHR (0.42) | ALDH1A1TSHRAOC3RAB9AG6PC1 | |
| SCHEMBL16492483 | 0.75 | TSHR (0.38) | ALDH1A1TSHRMEN1KMT2AAOC3 | |
| SCHEMBL15439602 | 0.73 | MAOB (0.34) | ALDH1A1TSHRMEN1KMT2AAOC3 | |
| SCHEMBL15440034 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRMEN1KMT2AAOC3 | |
| SCHEMBL15440161 | 0.72 | G6PC1 (0.36) | ALDH1A1KMT2ATDP1L3MBTL1G6PC1 | |
| SCHEMBL14799568 | 0.71 | TSHR (0.41) | ALDH1A1TSHRKMT2AAOC3RAB9A | |
| SCHEMBL16492407 | 0.70 | — | — | |
| SCHEMBL15440189 | 0.70 | TSHR (0.36) | ALDH1A1TSHRMEN1KMT2AAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |