Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14800157 | 0.89 | TSHR (0.39) | MAOBTSHRALDH1A1AOC3NPC1 | |
| SCHEMBL15439693 | 0.80 | TSHR (0.41) | MAOBBCHEACHETSHRALDH1A1 | |
| SCHEMBL15439386 | 0.80 | G6PC1 (0.40) | MAOBBCHEACHETSHRALDH1A1 | |
| SCHEMBL15439609 | 0.77 | TSHR (0.34) | MAOBBCHEACHETSHRALDH1A1 | |
| SCHEMBL15439796 | 0.76 | ALDH1A1 (0.32) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL14799603 | 0.76 | TSHR (0.42) | MAOBTSHRALDH1A1AOC3NPC1 | |
| SCHEMBL15440189 | 0.76 | TSHR (0.36) | MAOBTSHRALDH1A1AOC3NPC1 | |
| SCHEMBL14799774 | 0.73 | ALDH1A1 (0.34) | TSHRALDH1A1AOC3RAB9AKMT2A | |
| SCHEMBL15439473 | 0.72 | MAPT (0.40) | TSHRALDH1A1AOC3RAB9ALMNA | |
| SCHEMBL15439475 | 0.72 | MAPT (0.40) | TSHRALDH1A1AOC3RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |